PLPL3_MOUSE   Q91WW7


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UniProt:Q91WW7

Recommended name:1-acylglycerol-3-phosphate O-acyltransferase Pnpla3

EC number:EC 2.3.1.51

Alternative names:(Acylglycerol transacylase) (Adiponutrin) (ADPN) (Calcium-independent phospholipase A2-epsilon) (iPLA2-epsilon) (Lysophosphatidic acid acyltransferase) (Patatin-like phospholipase domain-containing protein 3) (EC 3.1.1.3)

Cleaved into:

GeneID:116939

Gene names  (primary ):Pnpla3

Gene names  (synonym ):Adpn

Gene names  (ORF ):

Length:413

Mass:45772

Sequence:MYDPERRWSLSFAGCGFLGFYHVGATLCLSERAPHLLRDARTFFGCSAGALHAVTFVCSLPLGRIMEILMDLVRKARSRNIGTLHPFFNINKCIRDGLQESLPDNVHQVISGKVHISLTRVSDGENVLVSEFHSKDEVVDALVCSCFIPLFSGLIPPSFRGERYVDGGVSDNVPVLDAKTTITVSPFYGEHDICPKVKSTNFFHVNITNLSLRLCTGNLQLLTRALFPSDVKVMGELCYQGYLDAFRFLEENGICNGPQRSLSLSLVAPEACLENGKLVGDKVPVSLCFTDENIWETLSPELSTALSEAIKDREGYLSKVCNLLPVRILSYIMLPCSLPVESAIAAVHRLVTWLPDIQDDIQWLQWATSQVCARMTMCLLPSTRSRASKDDHRMLKHGHHPSPHKPQGNSAGL

Tissue specificity:Restricted to adipose tissue. Expressed in inguinal and epididymal white adipose tissues and in interscapular brown adipose tissue (PubMed:11431482). Also expressed in liver in response to high-sucrose diet (PubMed:22560221). {ECO:0000269|PubMed:11431482, ECO:0000269|PubMed:22560221}.

Induction:Up-regulated in response to high-sucrose diet. {ECO:0000269|PubMed:22560221}.

Developmental stage:

Protein families:


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