PLPL3_MOUSE Q91WW7
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UniProt:Q91WW7
Recommended name:1-acylglycerol-3-phosphate O-acyltransferase Pnpla3
EC number:EC 2.3.1.51
Alternative names:(Acylglycerol transacylase) (Adiponutrin) (ADPN) (Calcium-independent phospholipase A2-epsilon) (iPLA2-epsilon) (Lysophosphatidic acid acyltransferase) (Patatin-like phospholipase domain-containing protein 3) (EC 3.1.1.3)
Cleaved into:
GeneID:116939
Gene names (primary ):Pnpla3
Gene names (synonym ):Adpn
Gene names (ORF ):
Length:413
Mass:45772
Sequence:MYDPERRWSLSFAGCGFLGFYHVGATLCLSERAPHLLRDARTFFGCSAGALHAVTFVCSLPLGRIMEILMDLVRKARSRNIGTLHPFFNINKCIRDGLQESLPDNVHQVISGKVHISLTRVSDGENVLVSEFHSKDEVVDALVCSCFIPLFSGLIPPSFRGERYVDGGVSDNVPVLDAKTTITVSPFYGEHDICPKVKSTNFFHVNITNLSLRLCTGNLQLLTRALFPSDVKVMGELCYQGYLDAFRFLEENGICNGPQRSLSLSLVAPEACLENGKLVGDKVPVSLCFTDENIWETLSPELSTALSEAIKDREGYLSKVCNLLPVRILSYIMLPCSLPVESAIAAVHRLVTWLPDIQDDIQWLQWATSQVCARMTMCLLPSTRSRASKDDHRMLKHGHHPSPHKPQGNSAGL
Tissue specificity:Restricted to adipose tissue. Expressed in inguinal and epididymal white adipose tissues and in interscapular brown adipose tissue (PubMed:11431482). Also expressed in liver in response to high-sucrose diet (PubMed:22560221). {ECO:0000269|PubMed:11431482, ECO:0000269|PubMed:22560221}.
Induction:Up-regulated in response to high-sucrose diet. {ECO:0000269|PubMed:22560221}.
Developmental stage:
Protein families: