IL23A_MOUSE Q9EQ14
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UniProt:Q9EQ14
Recommended name:Interleukin-23 subunit alpha
EC number:
Alternative names:(IL-23 subunit alpha) (IL-23-A) (Interleukin-23 subunit p19) (IL-23p19)
Cleaved into:
GeneID:83430
Gene names (primary ):Il23a
Gene names (synonym ):
Gene names (ORF ):
Length:196
Mass:22071
Sequence:MLDCRAVIMLWLLPWVTQGLAVPRSSSPDWAQCQQLSRNLCMLAWNAHAPAGHMNLLREEEDEETKNNVPRIQCEDGCDPQGLKDNSQFCLQRIRQGLAFYKHLLDSDIFKGEPALLPDSPMEQLHTSLLGLSQLLQPEDHPRETQQMPSLSSSQQWQRPLLRSKILRSLQAFLAIAARVFAHGAATLTEPLVPTA
Tissue specificity:Secreted by activated dendritic cells (at protein level). Detected in various tissues with higher expression in polarized Th1 cells and activated macrophages. {ECO:0000269|PubMed:11114383}.
Induction:Up-regulated in trigeminal glanglia after herpes simplex virus type 1 infection, in the lung of mice infected with mycobacteria or Klebsiella pneumoniae. Up-regulated in microglia by combined LPS and IFNG stimulation. Up-regulated by FASLG. {ECO:0000269|PubMed:11801672, ECO:0000269|PubMed:12162874, ECO:0000269|PubMed:14568135, ECO:0000269|PubMed:16339539}.
Developmental stage:
Protein families:IL-6 superfamily