BRNP3_MOUSE Q499E0
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UniProt:Q499E0
Recommended name：BMP/retinoic acid-inducible neural-specific protein 3
EC number：
Alternative names：
Cleaved into：
GeneID：215378
Gene names (primary )：Brinp3
Gene names (synonym )：Fam5c
Gene names (ORF )：
Length：766
Mass：88483
Sequence：MIWRRRAGAELSSLMALWEWIVLSLHCWVLAVAAVSDQHATSPFDWLLSDKGPFHRSQEYTDFVDRSRQGFSTRYKIYREFGRWKVNNLAVERRNFLGSPLPLAPEFFRNIRLLGRRPTLQQITENLIKKYGTHFLLSATLGGEESLTIFVDKRKLSKRSEGSETSTNSSSVTLETLHQLAASYFIDRDSTLRRLHHIQIASTAIKVTETRTGPLGCSNYDNLDSVSSVLVQSPENKIQLQGLQVLLPDYLQERFVQAALSYIACNSEGEFICKDNDCWCHCGPKFPECNCPSMDIQAMEENLLRITETWKAYNSDFEDSDEFKFFMKRLPMNYFLNTSTIMHLWTMDSNFQRRYEQLENSMKQLFLKAHRIVHKLFSLSKRCHKQPLISLPRQRTSTYWLTRIQSFLYCNENGLLGSFSEETHSCTCPNDQVVCTAFLPCTVGDASACLTCAPDNRTRCGTCNTGYMLSQGLCKPEVAESTDHYIGFETDLQDLEMKYLLQKTDRRIEVHAIFISNDMRLNSWFDPSWRKRMLLTLKSNKYKSSLVHMILGLSLQICLTKNSTLEPVLAVYVNPFGGSHSESWFMPVSESSFPDWERTKLDLPLQCYNWTLTLGNKWKTFFETVHIYLRSRIKANGPNSNESIYYEPLEFIDPSRNLGYMKINNIQVFGYSMHFDPEAIRDLILQLDYPYTQGSQDSALLQLLEIRDRVNKLSPPGQRRLDLFSCLLRHRLKLSTSEVVRIQSALQAFNAKLPNTVDYDTTKLCS
Tissue specificity：Expressed in the brain. Weakly expressed in embryonic stem (ES) cells. Expressed in ES-derived neural stem cells (NSCs) and neuronal cells. {ECO:0000269|PubMed:17138656, ECO:0000269|PubMed:20025061}.
Induction：Up-regulated upon differentiation into neuronal cells in the presence of retinoic acid and BDNF. Down-regulated upon differentiation into astroglial cells. Down-regulated in gonadotrope cells by bone morphogenetic protein and retinoic acid. {ECO:0000269|PubMed:17138656, ECO:0000269|PubMed:20025061}.
Developmental stage：
Protein families：BRINP family