RFFL_MOUSE Q6ZQM0
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UniProt:Q6ZQM0
Recommended name:E3 ubiquitin-protein ligase rififylin
EC number:EC 2.3.2.27
Alternative names:(RING finger and FYVE-like domain-containing protein 1) (Fring) (RING-type E3 ubiquitin transferase rififylin)
Cleaved into:
GeneID:67338
Gene names (primary ):Rffl
Gene names (synonym ):
Gene names (ORF ):
Length:377
Mass:42249
Sequence:MSQPSLWKDSHYFIMWASCCNWFCLDGQPEEAPPPQGARTQAYSNPGYSSFPSPTGSEPSCKACGVHFASTTRKQTCLDCKKNFCMTCSSQEGNGPRLCLLCLRFRATAFQREELMKMKVKDLRDYLSLHDISTEMCREKEELVFLVLGQQPVISEADRTRVPHLPQAFPEQQAFLTQPQTSTVPPTSPGLPSSPAQVTSVPLAQDQETQQAVGHVSQDHEEPIFPESTARVPTEDETQSVDSEDSFVPGRRASLSDLTHLEDIEGLTVRQLKEILARNFVNYKGCCEKWELMERVTRLYKDQKGLQHLVSGNEDQNGGAVPSGLEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICRQYVIRAVHVFRS
Tissue specificity:Ubiquitous. Detected in heart, brain, spleen, lung, liver, skeletal muscle, kidney, testis, thymus, whole embryo and embryonic stem cells. {ECO:0000269|PubMed:15229288}.
Induction:Up-regulation by LPA/lysophosphatidic acid is dependent on GNA12. {ECO:0000269|PubMed:22609986}.
Developmental stage:
Protein families: