RFFL_MOUSE   Q6ZQM0


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UniProt:Q6ZQM0

Recommended name:E3 ubiquitin-protein ligase rififylin

EC number:EC 2.3.2.27

Alternative names:(RING finger and FYVE-like domain-containing protein 1) (Fring) (RING-type E3 ubiquitin transferase rififylin)

Cleaved into:

GeneID:67338

Gene names  (primary ):Rffl

Gene names  (synonym ):

Gene names  (ORF ):

Length:377

Mass:42249

Sequence:MSQPSLWKDSHYFIMWASCCNWFCLDGQPEEAPPPQGARTQAYSNPGYSSFPSPTGSEPSCKACGVHFASTTRKQTCLDCKKNFCMTCSSQEGNGPRLCLLCLRFRATAFQREELMKMKVKDLRDYLSLHDISTEMCREKEELVFLVLGQQPVISEADRTRVPHLPQAFPEQQAFLTQPQTSTVPPTSPGLPSSPAQVTSVPLAQDQETQQAVGHVSQDHEEPIFPESTARVPTEDETQSVDSEDSFVPGRRASLSDLTHLEDIEGLTVRQLKEILARNFVNYKGCCEKWELMERVTRLYKDQKGLQHLVSGNEDQNGGAVPSGLEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICRQYVIRAVHVFRS

Tissue specificity:Ubiquitous. Detected in heart, brain, spleen, lung, liver, skeletal muscle, kidney, testis, thymus, whole embryo and embryonic stem cells. {ECO:0000269|PubMed:15229288}.

Induction:Up-regulation by LPA/lysophosphatidic acid is dependent on GNA12. {ECO:0000269|PubMed:22609986}.

Developmental stage:

Protein families:


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