MEIKN_MOUSE   Q5F2C3


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UniProt:Q5F2C3

Recommended name:Meiosis-specific kinetochore protein

EC number:

Alternative names:

Cleaved into:

GeneID:74847

Gene names  (primary ):Meikin

Gene names  (synonym ):

Gene names  (ORF ):

Length:434

Mass:47423

Sequence:MDKIWHMGPRGDYTRKKRAGERLNLTPKPDLALPGRTEALPGLKGKGKEQGLRKITEKKELSRLTGSSSQRPSLLSVTGGEHLQENSPGQETPEEKTPPCETVTDTFEMDSLLSSTELVSGPAEQDDFSSCLPSCSNAELHTESTDERGSSFPSPELFRGSDCLDWEHPKLEDYMFYKNSTLLDTSKAVVIEKAPQFANLSAVLSSSSKNYEKRHRKIGMTLAAQHLSPEPKYASNLASVVDNAASEVVFAEKTGPPTTEKTQKKPENESEDSGPLVQTKLSSGHPDNKALCSPLSSALESTAVRYTLLPQPLEPVLKKGCILPDKQSKALLTSTPSSDIAEFVIDLSPVQNVSFEELFPNVSNYVNSSEVVPVSSLQESSSNEFSPNTSEICCIIRSSPGTRQMRRKDPAVKNRCSPPKDVPLDIIMKTNGRT

Tissue specificity:Germ cell-specific. Expressed in both testis and ovary. Not expressed in other tissues. {ECO:0000269|PubMed:25533956}.

Induction:

Developmental stage:Appears at centromeres during the pachytene stage, when homologous chromosomes are synapsed. Peaks during diplotene stage, persists with gradual reduction until metaphase I, and disappears in anaphase I. Does not reappear on chromatin in meiosis II. {ECO:0000269|PubMed:25533956}.

Protein families:


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