MEIKN_MOUSE Q5F2C3
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UniProt:Q5F2C3
Recommended name:Meiosis-specific kinetochore protein
EC number:
Alternative names:
Cleaved into:
GeneID:74847
Gene names (primary ):Meikin
Gene names (synonym ):
Gene names (ORF ):
Length:434
Mass:47423
Sequence:MDKIWHMGPRGDYTRKKRAGERLNLTPKPDLALPGRTEALPGLKGKGKEQGLRKITEKKELSRLTGSSSQRPSLLSVTGGEHLQENSPGQETPEEKTPPCETVTDTFEMDSLLSSTELVSGPAEQDDFSSCLPSCSNAELHTESTDERGSSFPSPELFRGSDCLDWEHPKLEDYMFYKNSTLLDTSKAVVIEKAPQFANLSAVLSSSSKNYEKRHRKIGMTLAAQHLSPEPKYASNLASVVDNAASEVVFAEKTGPPTTEKTQKKPENESEDSGPLVQTKLSSGHPDNKALCSPLSSALESTAVRYTLLPQPLEPVLKKGCILPDKQSKALLTSTPSSDIAEFVIDLSPVQNVSFEELFPNVSNYVNSSEVVPVSSLQESSSNEFSPNTSEICCIIRSSPGTRQMRRKDPAVKNRCSPPKDVPLDIIMKTNGRT
Tissue specificity:Germ cell-specific. Expressed in both testis and ovary. Not expressed in other tissues. {ECO:0000269|PubMed:25533956}.
Induction:
Developmental stage:Appears at centromeres during the pachytene stage, when homologous chromosomes are synapsed. Peaks during diplotene stage, persists with gradual reduction until metaphase I, and disappears in anaphase I. Does not reappear on chromatin in meiosis II. {ECO:0000269|PubMed:25533956}.
Protein families: