SPRN_MOUSE Q8BWU1
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UniProt:Q8BWU1
Recommended name:Shadow of prion protein
EC number:
Alternative names:(Protein shadoo)
Cleaved into:
GeneID:212518
Gene names (primary ):Sprn
Gene names (synonym ):Gm169
Gene names (ORF ):
Length:147
Mass:14591
Sequence:MNWTAATCWALLLAAAFLCDSCSAKGGRGGARGSARGVRGGARGASRVRVRPAPRYGSSLRVAAAGAAAGAAAGVAAGLATGSGWRRTSGPGELGLEDDENGAMGGNGTDRGVYSYWAWTSGSGSVHSPRICLLLGGTLGALELLRP
Tissue specificity:Mainly expressed in brain (at protein level). In brain, it is highly expressed in the hippocampus and cerebellum and is also expressed at lower level in other areas of the brain including the cerebral cortex, the thalamus and the medulla. In hippocampus and cerebellum it is highly expressed in the cell bodies of pyramidal cells and Purkinje cells, respectively. {ECO:0000269|PubMed:17703189}.
Induction:Strongly down-regulated in prion-infected brains (at protein level). {ECO:0000269|PubMed:17703189}.
Developmental stage:Appears at embryonic day 16 and persists in early postnatal life and in the brains of adults (at protein level). {ECO:0000269|PubMed:17703189}.
Protein families:SPRN family