MB211_MOUSE   O70299


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UniProt:O70299

Recommended name:Putative nucleotidyltransferase MAB21L1

EC number:EC 2.7.7.-

Alternative names:(Protein mab-21-like 1)

Cleaved into:

GeneID:17116

Gene names  (primary ):Mab21l1

Gene names  (synonym ):Mab21

Gene names  (ORF ):

Length:359

Mass:40956

Sequence:MIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECHSLAGKQSSAESDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL

Tissue specificity:Expressed in the adult cerebellum and eye, with lower levels in the adult forebrain. {ECO:0000269|PubMed:10349626, ECO:0000269|PubMed:10556287}.

Induction:Expression is down-regulated by BMP2. {ECO:0000269|PubMed:17167770}.

Developmental stage:At 10 dpc, expressed in the temporal aspect of the retina and the anterior portion of the alar midbrain. At 10.5 dpc this retinal pattern of expression persists, with expression also beginning in the lens. Also expressed in the spinal cord, the optic cup, the presumptive lens and the genital ridge. Expressed in the dorsal midline, somites, and interdigital tissues from 9.5 dpc to 13.5 dpc. {ECO:0000269|PubMed:10349626, ECO:0000269|PubMed:10556287, ECO:0000269|PubMed:12642482}.

Protein families:Mab-21 family


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