SPHK1_MOUSE Q8CI15
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UniProt:Q8CI15
Recommended name:Sphingosine kinase 1
EC number:EC 2.7.1.91
Alternative names:(SK 1) (SPK 1) (Acetyltransferase SPHK1) (EC 2.3.1.-)
Cleaved into:
GeneID:20698
Gene names (primary ):Sphk1
Gene names (synonym ):Sk1
Gene names (ORF ):
Length:382
Mass:42443
Sequence:MEPVECPRGLLPRPCRVLVLLNPQGGKGKALQLFQSRVQPFLEEAEITFKLILTERKNHARELVCAEELGHWDALAVMSGDGLMHEVVNGLMERPDWETAIQKPLCSLPGGSGNALAASVNHYAGYEQVTNEDLLINCTLLLCRRRLSPMNLLSLHTASGLRLYSVLSLSWGFVADVDLESEKYRRLGEIRFTVGTFFRLASLRIYQGQLAYLPVGTVASKRPASTLVQKGPVDTHLVPLEEPVPSHWTVVPEQDFVLVLVLLHTHLSSELFAAPMGRCEAGVMHLFYVRAGVSRAALLRLFLAMQKGKHMELDCPYLVHVPVVAFRLEPRSQRGVFSVDGELMVCEAVQGQVHPNYLWMVCGSRDAPSGRDSRRGPPPEEP
Tissue specificity:Widely expressed (PubMed:9726979). Expressed in brain (at protein level). Detected in neurons. {ECO:0000269|PubMed:29662056, ECO:0000269|PubMed:9726979}.
Induction:
Developmental stage:At 10.5 dpc, expressed in the whole brain, with the highest levels in the telencephalon. {ECO:0000269|PubMed:16314531}.
Protein families: