CKP2L_MOUSE Q7TS74
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UniProt:Q7TS74
Recommended name：Cytoskeleton-associated protein 2-like
EC number：
Alternative names：(Radial fiber and mitotic spindle protein) (Radmis)
Cleaved into：
GeneID：70466
Gene names (primary )：Ckap2l
Gene names (synonym )：
Gene names (ORF )：
Length：745
Mass：82999
Sequence：MVGPGPTASAAAEERWQKLQEYLAAKGKLKDPNAKPYLKAKNICPKPPPSKYTPGPKKDVSNHVLPSKTTRPINIKFQTKPASITASQKPESKPPKLPSRGLTSRCFSSNTDCKQSSKPQQQPRAVSFTAGLSRNPRQCPDIQELKTKQQQQAHGGNAKCTHPETNTHAAKQPVDGFPDETNKENLPQALPKPEKPDPELHSIRKPNTGSSNQTQKGLAPKQILSKSSVTQTALKDRANKQFIRNTQIRTQAVKSRPRPTVADSTRPREKPPQTAPSHSVPAHNKTQTSKKPMTKNTQDITVNRVRYGKPNETKIESCPATEQKVKHTKPSSQLNVLQGGHNSRHPNMRQDQKPVQPHLGPQTSCVLQKSRAISQRPNLTARNFNSVIPSTPNMRANKTLNNKYNNIFQQKAQTLDSKFRKFPPQSHFLNKTAPRTQASTAAASRKGAPSATQTHPHGKKPEGEDRRKQLEEWQKSKGKTYKRPPMKFKTKRKVIEEMNTSFWKSIEREEEEKKAQLELSKKIDSTLTECLRLIEEGVLPNEIFTIVSSIPEAEKFAKFWVCKAKLLASKGTFDAIGLYEEAIQNGATPVQELQEVLNVLQDPCRSTEAVTSDTSAAGTNTTSAEELAKEESEQPCPSLTEMEPIAAAAPRIPVSEWDNHGIKLQVAPIPRICGMPEVQDMKLITPVRRSARIERTVARYPEMLQEHDVVVASLNELLEVDKTECFIFRENEALPVTLGFEVLES
Tissue specificity：Highly expressed in regions of active neurogenesis and neural stem/progenitor cells (NSPCs), both embryonic and adult, not detected in lung, liver, kidney, heart, and skeletal muscle. {ECO:0000269|PubMed:24260314}.
Induction：
Developmental stage：At 10.5 dpc, strongly expressed in the neural progenitor cells throughout the neural tube and in the myotome. Expression is significantly lower in connective tissues compared to neural tube, but can be detected at the mitotic spindles of dividing mesenchymal cells loosely distributed in the developing limb bud. In an 12.5 dpc forelimb bud, detected in the dividing cells at the boundary region between protruding cartilage and surrounding mesenchyme (at protein level). {ECO:0000269|PubMed:25439729}.
Protein families：CKAP2 family