NSMF_MOUSE Q99NF2
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UniProt:Q99NF2
Recommended name：NMDA receptor synaptonuclear signaling and neuronal migration factor
EC number：
Alternative names：(Juxtasynaptic attractor of caldendrin on dendritic boutons protein) (Jacob protein) (Nasal embryonic luteinizing hormone-releasing hormone factor) (Nasal embryonic LHRH factor)
Cleaved into：
GeneID：56876
Gene names (primary )：Nsmf
Gene names (synonym )：Jac Nelf
Gene names (ORF )：
Length：532
Mass：60293
Sequence：MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHDGSPEMQPAPQNKRRLSLVSNGRYEGSISDEAVSGKPAIEGPQPHVYTISREPALLPGSEAEAIELAVVKGRRQRERHPHHHSQPLRASPGSSREDISRPCQSWAGSRQGSKECPGCAQLVPGPSSRAFGLEQPPLPEAPGRHKKLERMYSVDGVSDDVPIRTWFPKENLFSFQTATTTMQAISVFRGYAERKRRKRENDSASVIQRNFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPMKADTSHDSRDSSDLQSSHCTLDEACEDLDWDTEKGLEAMACNTEGFLPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIEKKLNIYHKGAKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHFWKRLSRLMSKVNPEPNVIHIMGCYILGNPNGEKLFQNLRTLMTPYKVTFESPLELSAQGKQMIETYFDFRLYRLWKSRQHSKLLDFDDVL
Tissue specificity：Preferentially expressed in immature migratory, in comparison to postmigrating, gonadotropin-releasing hormone (GnRH) neuronal cell lines (at protein level). Expressed in adult brain and liver. In the brain, expressed in the primary pituitary gland, cortex, hippocampus, olfactory bulb and thalamus. {ECO:0000269|PubMed:10898796, ECO:0000269|PubMed:15018815, ECO:0000269|PubMed:20025934}.
Induction：Up-regulated by gonadotropin releasing hormone (GnRH). {ECO:0000269|PubMed:20025934}.
Developmental stage：At 14.5 dpc embryo found at high levels within the forebrain, olfactory epithelium and olfactory pit. At 12.5 dpc embryo detected on olfactory axons including olfactory pathway on which the LHRH neurons move. From 11.5 dpc to 17.5 dpc embryos expressed in LHRH (luteinizing hormone-releasing hormone) neurons as they migrate from the olfactory pit into the developing forebrain. {ECO:0000269|PubMed:10898796}.
Protein families：NSMF family