SNORC_MOUSE Q9CXL7
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UniProt:Q9CXL7
Recommended name:Protein SNORC
EC number:
Alternative names:(Secondary ossification center-associated regulator of chondrocyte maturation protein)
Cleaved into:
GeneID:73234
Gene names (primary ):Snorc
Gene names (synonym ):
Gene names (ORF ):
Length:121
Mass:12175
Sequence:MASCLALRVALLLISGVLAPAVLTAEGPQEPDPTLWNEPIELPSGEGPLESTSHNQEFAVSGPPFPTSAPAPEDSTPPARVDQDGGSLGPGAIAAIVIAALLATCVVLALVVVALRKFSAS
Tissue specificity:Expressed only in cartilage, including nasal, knee epiphyseal and rib tissues (PubMed:21624478). In proliferation and hypertrophic chondrocytes, detected intracellulary and in the pericellular extracellular matrix. In primary spongiosa, detected only in the extracellular matrix (PubMed:28323137). {ECO:0000269|PubMed:21624478, ECO:0000269|PubMed:28323137}.
Induction:In chondrocytes, induced by BMP2. {ECO:0000269|PubMed:21624478}.
Developmental stage:At 16.5 dpc and 18.5 dpc expression is cartilage specific. In tracheal and nasal cartilage, expression is seen throughout all chondrocytes at a similar intensity while in other cartilage tissues undergoing endochondral ossification, intensity is strongest in proliferating and prehypertrophic stages. In knee epiphyseal cartilage, expression is detected from 12.5 dpc onwards, with significant up-regulation at 16.5 dpc and again at postnatal day 5. Expressed at least until 10 months of age. {ECO:0000269|PubMed:21624478}.
Protein families: