PRD14_MOUSE E9Q3T6
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UniProt:E9Q3T6
Recommended name：PR domain zinc finger protein 14
EC number：EC 2.1.1.-
Alternative names：(PR domain-containing protein 14)
Cleaved into：
GeneID：383491
Gene names (primary )：Prdm14
Gene names (synonym )：
Gene names (ORF )：
Length：561
Mass：63374
Sequence：MALPPSGETQSQDKANYLPQSNPHHLTTYYAHAPGYSHFRNLATTEEEFQPWKLAAAVLESQAMAPLDAFRMTAPLLNPGLAVQSEPLYNLPWYKLSPWNRIPQFTPEVPRFLDSTEHRSSGSSNQNLVLGGGGGQISGQRWEAENLLLPSPVIASLLPDGIKSSQSISVPQTLNQEGKLPFCGFNFTEEELSFVLYGAIASPEHPTDLQHAISGILVPTESSGSNHLHKTLDKDSLQLPEGLCLMQTSFGDVPHFGVFCSDFIAKGVRFGPFRGRVVNASEVKAHRDNSRMWEIFEDGHLSHFIDGKGSGNWMSYVNCARFPKEQNLLAVQHQGQIFYESCRDIQRNQELLVWYGNGYEKFLGVPMNLRVTEQGGQQLSESSEESAEGYRCERCGKVFTYKYYRDKHLKYTPCVDKGDRKFPCSLCQRSFEKRDRLRIHILHVHERHRPYLCSTCGKSFSQSSSLNKHMRVHSGDRPYQCVYCTKKFTASSILRTHIRQHSGEKPFKCKHCGKAFASHAAHDSHVRRSHKDNGRSSCDICGKGFLDQEAFYAHMRLHKTC
Tissue specificity：Restricted to embryonic stem cells and primordial germ cells. Not detected in epiblast-derived stem cells. {ECO:0000269|PubMed:18622394, ECO:0000269|PubMed:20953172}.
Induction：
Developmental stage：At 3.5 dpc, weak and transient expression in the inner cell mass cells of blastocysts. This expression disappears by 5.5 dpc. Expression starts again in committed PGCs around 6.5 dpc in the extraembryonic mesoderm contiguous from the most proximal epiblast (at protein level). Expression persists specifically in PGCs until about 13.5-14.5 dpc both in females and males. {ECO:0000269|PubMed:18622394}.
Protein families：Class V-like SAM-binding methyltransferase superfamily