SCX_MOUSE Q64124
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UniProt:Q64124
Recommended name：Basic helix-loop-helix transcription factor scleraxis
EC number：
Alternative names：
Cleaved into：
GeneID：20289
Gene names (primary )：Scx
Gene names (synonym )：
Gene names (ORF )：
Length：207
Mass：22239
Sequence：MSFAMLRSAPPPGRYLYPEVSPLSEDEDRGSESSGSDEKPCRVHAARCGLQGARRRAGGRRAAGSGPGPGGRPGREPRQRHTANARERDRTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLVGEACGDGQPCHSGPAFFHSGRAGSPLPPPPPPPPLARDGGENTQPKQICTFCLSNQRKLSKDRDRKTAIRS
Tissue specificity：Expressed in mesenchymal precursors of cartilage and in connective tissue. Highly expressed in tendons in the limb, tongue and diaphragm and in cartilage of the bronchi.
Induction：
Developmental stage：At 6.0-6.5 dpc, expressed throughout the egg cylinder with highest expression in the epiblast. At 9.5-10.5 dpc, expressed in the lateral sclerotome and in mesenchymal cells of the limb buds and body wall. At 11.0 dpc, expressed in a metameric pattern extending along the length of the embryo. By 11.5 dpc, expression in the developing vertebrae and invertebral disks is extended caudally. High expression was seen in precursors of the ribs and bones of the limbs. Expression in progenitors of the ribs and the axial and appendicular skeleton becomes down-regulated when ossification is initiated.
Protein families：