SEPT9_MOUSE Q80UG5
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UniProt:Q80UG5
Recommended name：Septin-9
EC number：
Alternative names：(SL3-3 integration site 1 protein)
Cleaved into：
GeneID：53860
Gene names (primary )：Septin9
Gene names (synonym )：Kiaa0991 Sept9 Sint1
Gene names (ORF )：
Length：583
Mass：65575
Sequence：MKKSYSGVTRTSSGRLRRLADPTGPALKRSFEVEEIEPPNSTPPRRVQTPLLRATVASSSQKFQDLGVKNSEPAARLVDSLSQRSPKPSLRRVELAGAKAPEPMSRRTEISIDISSKQVESTASAAGPSRFGLKRAEVLGHKTPEPVPRRTEITIVKPQESVLRRVETPASKIPEGSAVPATDAAPKRVEIQVPKPAEAPNCPLPSQTLENSEAPMSQLQSRLEPRPSVAEVPYRNQEDSEVTPSCVGDMADNPRDAMLKQAPASRNEKAPMEFGYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERVYFKQRITADLLSNGIDVYPQKEFDEDAEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSNIHFEAYRVKRLNEGNSAMANGIEKEPEAQEM
Tissue specificity：Expressed in all tissues examined except muscle. Isoforms are differentially expressed in testes, kidney, liver, heart, spleen and brain. {ECO:0000269|PubMed:10666245, ECO:0000269|PubMed:12039034}.
Induction：
Developmental stage：At 8 dpc mainly expressed in the lateral plate mesoderm and the somites. Beginning at 9 dpc the lateral plate expression is clearly focused in the developing fore- and hindlimb buds. In the cephalic region, expressed in the first and second branchial arch, in the nasal process and around the otic pit. At 9.5 dpc strongest expression is observed in the mesenchyme of the branchial arches, the limbs, and the developing dorsal root ganglia. Weak to intermediate expression is found in the neural epithelium. Expression is seen in the newly formed somites in the tail bud of older embryos. During formation of the digits, expression seems to outline the surviving tissue bordering it towards the apoptotic webbing. Expression is seen in the developing outer ear and in several areas known to be regulated by intensive epithelial mesenchymal interactions, like the viscera follicles and the developing mammary glands. {ECO:0000269|PubMed:12039034}.
Protein families：TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family