IGF2_MOUSE P09535
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UniProt:P09535
Recommended name：Insulin-like growth factor II
EC number：
Alternative names：(IGF-II) (Multiplication-stimulating polypeptide)
Cleaved into：Insulin-like growth factor II; Preptin
GeneID：16002
Gene names (primary )：Igf2
Gene names (synonym )：Igf-2
Gene names (ORF )：
Length：180
Mass：20030
Sequence：MGIPVGKSMLVLLISLAFALCCIAAYGPGETLCGGELVDTLQFVCSDRGFYFSRPSSRANRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTSQAVLPDDFPRYPVGKFFQYDTWRQSAGRLRRGLPALLRARRGRMLAKELKEFREAKRHRPLIVLPPKDPAHGGASSEMSSNHQ
Tissue specificity：Expressed in the heart, blood serum, kidney and skeletal muscle including the tibialis anterior muscle. {ECO:0000269|PubMed:29440408}.
Induction：
Developmental stage：At 8 dpc, 9.5 dpc and 16.5 dpc, transcripts from parental allele are detected in embryonic and extraembryonic tissues (PubMed:28522536, PubMed:1997210). At 16.5 dpc, transcripts from parental and maternal alleles are detected only in the choroid plexus and the leptomeninges (PubMed:1997210). Expressed in fetal muscle and brain tissue at 12.5 dpc (PubMed:29440408). Low levels of expression during myoblast proliferation. Levels rise rapidly during myoblast differentiation and then decrease. {ECO:0000269|PubMed:1997210, ECO:0000269|PubMed:28522536, ECO:0000269|PubMed:29440408}.; [Isoform 2]: Predominant isoform expressed in fetal muscle tissues at 12.5 dpc. {ECO:0000269|PubMed:29440408}.
Protein families：Insulin family