RFX4_MOUSE Q7TNK1
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UniProt:Q7TNK1
Recommended name:Transcription factor RFX4
EC number:
Alternative names:(Regulatory factor X 4)
Cleaved into:
GeneID:71137
Gene names (primary ):Rfx4
Gene names (synonym ):
Gene names (ORF ):
Length:735
Mass:83371
Sequence:MHCGLLEEPDMDSTESWIERCLNESENKRYSSHTSLGNVSNDENEEKENNRASKPHSTPATLQWLEENYEIAEGVCIPRSALYMHYLDFCEKNDTQPVNAASFGKIIRQQFPQLTTRRLGTRGQSKYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKREVTKQTVAYSPRSKLGTLLPDFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHMLPVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLSSITKQTLYTMEDSRDEHRRLIIQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKRQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAMKGEGSTAEAQEEIILTEATPPTPSPGPSFSPAKSATSVEVPPPSSPVSNPSPEYTGLSTAGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRSTHMPSSSVTHRIPVYSHREEHGYTGSYNYGSYGNQHPHPLQNQYPALPHDTAISGPLHYSPYHRSSAQYPFNSPTSRMEPCLMSSTPRLHPTPVTPRWPEVPTANACYTSPSVHSTRYGNSSDMYTPLTTRRNSEYEHMQHFPGFAYINGEASTGWAK
Tissue specificity:Isoform 1: Brain-specific. Isoform 2: Testis-specific. Isoform 1: Highly expressed in the suprachiasmatic nucleus, the central pacemaker site of the circadian clock (at protein level). {ECO:0000269|PubMed:12925582, ECO:0000269|PubMed:14701801}.
Induction:[Isoform 1]: Induced in a subjective night-specific manner. {ECO:0000269|PubMed:14701801}.
Developmental stage:At 8.5 dpc, detected in most of the neural plate but is excluded from the presumptive forebrain region. At 9.5 dpc, its expression is mostly restricted to two large regions, the caudal diencephalon/mesencephalon and the spinal cord. By 10.5 dpc, is present throughout the neural tube, and it is also detected in the cerebral cortex. It is also strongly expressed in the developing subcommissural organ (SCO) from 14.5 dpc to birth. {ECO:0000269|PubMed:12925582}.
Protein families:RFX family