GRHL3_MOUSE Q5FWH3
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UniProt:Q5FWH3
Recommended name:Grainyhead-like protein 3 homolog
EC number:
Alternative names:(Transcription factor CP2-like 4)
Cleaved into:
GeneID:230824
Gene names (primary ):Grhl3
Gene names (synonym ):Get1 Som Tfcp2l4
Gene names (ORF ):
Length:603
Mass:67816
Sequence:MSNELDFRSVRLLKNDPVSFQKFPYSNEDEAWKTYLENPLTAATKAMMRVNGDEESVAALSFLYDYYMGPKEKRILSSSTGGRNDQGKKFYHSMDYEPDLAPLESPTHLMKFLTENVSGSPDYTDQLKKNNLLGLEGVLPTPGKTNTVPPGPSKLEASSMDSYLLPASDIYDNGSLNSLFESIHGVPPTQRWQPDSTFKDDPQESLLFPDILKTSPDPPCPEDYPGLKSDFEYTLGSPKAIHIKAGESPMAYLNKGQFYPVTLRTPAGGKGLALSSSKVKSVVMVVFDNDKVPVEQLRFWRHWHSRQPTAKQRVIDVADCKENFNTVQHIEEVAYNALSFVWNVNEEAKVFIGVNCLSTDFSSQKGVKGVPLNLQIDTYDCGAGTERLVHRAVCQIKIFCDKGAERKMRDDERKQFRRKVKCPDSSNNAGIKGCLLSGFRGNETTYLRPETDLETQPVLFIPNLHFSSLQRPGGVVPSAGHSSSDRLPLKRTCSPFAEEFEPLPSKQAKEDDLQRVLLYVRRETEEVFDALMLKTPDLKGLRNAISEKYGLPEENICKVYKKCKRGILVNMDNNIIQHYSNHVAFLLDMGELDGKIQIILKEL
Tissue specificity:
Induction:
Developmental stage:At 8.5 dpc, expression is confined to the non-neural ectoderm immediately adjacent to the neural plate, which was undergoing folding to form the neural tube. At later time points, more widespread expression is observed in the surface ectoderm, with a progressive increase until 15.5 dpc. Also expressed in other tissues lined by squamous epithelium, including the oral cavity, urogenital sinus and anal canal. {ECO:0000269|PubMed:14608380}.
Protein families:Grh/CP2 family, Grainyhead subfamily