RSLAB_MOUSE Q5SSG5
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UniProt:Q5SSG5
Recommended name:Ras-like protein family member 10B
EC number:EC 3.6.5.2
Alternative names:
Cleaved into:
GeneID:276952
Gene names (primary ):Rasl10b
Gene names (synonym ):
Gene names (ORF ):
Length:203
Mass:23229
Sequence:MVSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTTRRLYLPAVVMNGHVHDLQILDFPPISAFPVNTLQEWADACCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETPIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGCARCKHVHAALRFQGALRRNRCAIM
Tissue specificity:Expressed in heart and brain. In the brain, expression restricted to neurons of the cortex, hippocampus and cerebellum. Sparse expression in the brainstem and almost absent in the hypothalamic region. In the heart, expressed in cardiomyocytes. Not detected in interstitial tissue or vascular cells. {ECO:0000269|PubMed:17984325}.
Induction:
Developmental stage:At 9.5 dpc, detected in the developing heart, skeletal myotomes and dorsal portion of the neural tube. At 13.5 and 15.5 dpc, expressed in the heart and neural tissue including the central and peripheral nervous system. In the embryonic brain, expression is restricted to more mature neurons and absent from the progenitor neuronal cells of the ventricular zone. Also present in mature peripheral neurons, such as the neurons of the dorsal root ganglia and the Auerbach's and Meissner's plexi of the intestinal tract. {ECO:0000269|PubMed:17984325}.
Protein families:Small GTPase superfamily, Ras family