CEBPB_MOUSE P28033
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UniProt:P28033
Recommended name：CCAAT/enhancer-binding protein beta
EC number：
Alternative names：(C/EBP beta) (AGP/EBP) (Interleukin-6-dependent-binding protein) (IL-6DBP) (Liver-enriched transcriptional activator) (LAP)
Cleaved into：
GeneID：12608
Gene names (primary )：Cebpb
Gene names (synonym )：
Gene names (ORF )：
Length：296
Mass：31446
Sequence：MHRLLAWDAACLPPPPAAFRPMEVANFYYEPDCLAYGAKAARAAPRAPAAEPAIGEHERAIDFSPYLEPLAPAADFAAPAPAHHDFLSDLFADDYGAKPSKKPADYGYVSLGRAGAKAAPPACFPPPPPAALKAEPGFEPADCKRADDAPAMAAGFPFALRAYLGYQATPSGSSGSLSTSSSSSPPGTPSPADAKAAPAACFAGPPAAPAKAKAKKTVDKLSDEYKMRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTLRNLFKQLPEPLLASAGHC
Tissue specificity：Abundantly expressed in myoblasts. Enriched in brown adipose tissue (BAT) versus white adipose tissue (WAT). Expressed in hepatocytes (at protein level). Expressed in T lymphocytes (PubMed:16585579). The expression in granulosa cells of antral follicles is induced by luteinizing hormone (PubMed:9303532). Expressed in chondrocytes and osteoblasts (at protein level) (PubMed:19440205). {ECO:0000269|PubMed:10635333, ECO:0000269|PubMed:16585579, ECO:0000269|PubMed:19440205, ECO:0000269|PubMed:19641492, ECO:0000269|PubMed:9303532}.
Induction：Up-regulated by cold exposure. {ECO:0000269|PubMed:19641492}.
Developmental stage：At 9.5 dpc, expressed in the chorionic plate and ectoplacental cone. From 10.5 dpc to at least 11.5 dpc, is also expressed in the trophoblast cells of the three placenta layers (PubMed:15509779). Expressed in monocytic precursors but is vanished during differentiation into osteoclasts. The expression increases during osteoblast differentiation (PubMed:19440205). {ECO:0000269|PubMed:15509779, ECO:0000269|PubMed:19440205}.
Protein families：BZIP family, C/EBP subfamily