VAX2_MOUSE   Q9WTP9


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UniProt:Q9WTP9

Recommended name:Ventral anterior homeobox 2

EC number:

Alternative names:(Ventral retina homeodomain protein)

Cleaved into:

GeneID:24113

Gene names  (primary ):Vax2

Gene names  (synonym ):Vex

Gene names  (ORF ):

Length:292

Mass:31701

Sequence:MGDGGAERDRGPKRREEPGGRSGRHGEHRGAEDLRADTGSASPREIAGTSASSPAGSRESGGDSDGQQALGETDHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEAFATSNVLRLLEQGRLLSVPRAPSLLALTPGLPGLPASHRGTSLVDPRNSSPRLNPMPSASASSPLPPPLPAICFSSAPLLDLPAGYKLGSSAFEPYSRLEQQKVGSPGQSDKKADI

Tissue specificity:Expressed in the developing and mature retina. {ECO:0000269|PubMed:10421837, ECO:0000269|PubMed:10595508}.

Induction:

Developmental stage:At 9.5 dpc, expressed solely in the ventral halves of the optic stalks and vesicles without proximo-distal restriction. Expression in the optic stalk diminishes after 11.5 dpc and becomes restricted to the inner layer of optic cup in its ventral half. Expression persists in the ventral halves of all neural retina layers (inner and outer nuclear layer) at 14.5 dpc and 16.5 dpc, and the ganglion cell layer, inner nuclear layer and photoreceptor layer in the adult. {ECO:0000269|PubMed:10421837, ECO:0000269|PubMed:10485894}.

Protein families:EMX homeobox family


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