LFTY2_MOUSE P57785
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UniProt:P57785
Recommended name:Left-right determination factor 2
EC number:
Alternative names:(Left-right determination factor B) (Protein lefty-2) (Protein lefty-B)
Cleaved into:
GeneID:320202
Gene names (primary ):Lefty2
Gene names (synonym ):Leftb
Gene names (ORF ):
Length:368
Mass:41175
Sequence:MKSLWLCWALWVLPLAGPGAAMTEEQVLSSLLQQLQLSQAPTLDSADVEEMAIPTHVRSQYVALLQGSHADRSRGKRFSQNFREVAGRFLMSETSTHLLVFGMEQRLPPNSELVQAVLRLFQEPVPRTALRRFERLSPHSARARVTIEWLRVREDGSNRTALIDSRLVSIHESGWKAFDVTEAVNFWQQLSRPRQPLLLQVSVQREHLGPGTWSAHKLVRFAAQGTPDGKGQGEPQLELHTLDLKDYGAQGNCDPEVPVTEGTRCCRQEMYLDLQGMKWAENWILEPPGFLTYECVGSCLQLPESLTIGWPFLGPRQCVASEMTSLPMIVSVKEGGRTRPQVVSLPNMRVQTCSCASDGALIPRGIDL
Tissue specificity:
Induction:
Developmental stage:At the primitive streak stage (7.0 dpc), expressed in the emerging mesoderm. By 8.0 dpc, expressed exclusively on the left side of developing embryos with expression predominantly in the lateral-plate mesoderm (LPM). Weak expression in the prospective floor plate (PFP).
Protein families:TGF-beta family