ERF3B_MOUSE Q149F3
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UniProt:Q149F3
Recommended name:Eukaryotic peptide chain release factor GTP-binding subunit ERF3B
EC number:
Alternative names:(Eukaryotic peptide chain release factor subunit 3b) (eRF3b) (G1 to S phase transition protein 2 homolog)
Cleaved into:
GeneID:14853
Gene names (primary ):Gspt2
Gene names (synonym ):Erf3b
Gene names (ORF ):
Length:632
Mass:69147
Sequence:MDLGSSSDSAPDCWDQVDMEAPGSAPSGDGIAPAAMAAAEAAEAEAQRKHLSLAFSSQLNIHAKPFVPSVSAAEFVPSFLPGSAQPPAPTASSCDETCIGGAGEPEGKRMEWGAPVEPSKDGPLVSWEGSSSVVTMELSEPVVENGEVEMALEESWELKEVSEAKPEASLGDAGPPEESVKEVMEEKEEVRKSKSVSIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHSVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
Tissue specificity:Highly expressed in brain. Moderately expressed in spleen and lung. Weakly expressed in heart, liver and kidney. Expression during the cell-cycle progression is constant. {ECO:0000269|PubMed:9712840}.
Induction:
Developmental stage:Barely detectable at 15 dpc, increased after birth to reach a maximum at P15. {ECO:0000269|PubMed:15987998}.
Protein families:TRAFAC class translation factor GTPase superfamily, Classic translation factor GTPase family, ERF3 subfamily