CASC1_MOUSE   Q6TDU8


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UniProt:Q6TDU8

Recommended name:Dynein intermediate chain CFAP94, axonemal

EC number:

Alternative names:(Cancer susceptibility candidate gene 1 protein homolog) (Protein CASC1) (Cilia and flagella associated protein 94) (Lung adenoma susceptibility protein 1)

Cleaved into:

GeneID:320662

Gene names  (primary ):Cfap94

Gene names  (synonym ):Casc1 Las1

Gene names  (ORF ):

Length:730

Mass:84966

Sequence:MAPKSKKAPSKKKMTKAERLRLMQEEEERRLKEEEEARLKFEKEEQERLEIQRIEREKWNLLEKKDLERRSQELEELALLEGCFPEAEKQKREIRALAQWKHYTECDGSPDPWVAQEMNTFISLWEEEKNQAFEQVMEKSKLVLSLIEKVKLILLETPTYELDHRTVLQHQGSILRLQELLSLKINVATELLLRQASNLADLDTGNMEKIIKDENVTLYVWANLKKNPRHRSVRFSETQIGFEIPRILATSNVALRLLHTRYDHITPLFPIAVTEQNQNPVGAEQVNVEESTEKAMTEEKLFTEEKAANEDEQPKAEQERELNLVQEENKYEAIENTVLQRTSDSEGEDSQTTQLELEMKLLSEAVLAAQLCLVENVVELPEASQAYKVDLCHFSTLGGVYHLDVLELPPQCKPVKGWVLVEILQEGLQRFIYPPDTTEEPDPDVTFPPIEVTLEIHKSVIFFERPRVVRWDNEGKFWRSDGISSVYYNREDRLLTFSMDTLGPVTLIQDAHVNMPYQSWEMSPCGMNKVLLIVKTVFMELQIYIKENLCMLASVKLRGKGLEFHLKGKWMAPIPFILALKEAGLNIFPAVYSHFYVVINNKVPQVELKAYRQMALLSSAFSFGWSKWNMVCNSTRVVIRVREQLSEETEHHTWSLLMFSGDRAQMLKMQEENDKFSEALREGTEFHSTLYHMMKDFASPVAMERVRHSNCQFIDSVCYMLLSIRVLSYS

Tissue specificity:High expressed in lung, kidney, and testis. {ECO:0000269|PubMed:14583591}.

Induction:

Developmental stage:Cell cycle-dependent expression. Not detected in G0 cells, starts to accumulate in early S phase, reaches the highest level in the G2 phase, and drops to very low levels at mitosis. {ECO:0000269|PubMed:17974961}.

Protein families:CFAP94 family


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