CP2E1_MOUSE Q05421
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UniProt:Q05421
Recommended name:Cytochrome P450 2E1
EC number:EC 1.14.14.1
Alternative names:(4-nitrophenol 2-hydroxylase) (CYPIIE1) (Cytochrome P450-ALC) (Cytochrome P450-J)
Cleaved into:
GeneID:13106
Gene names (primary ):Cyp2e1
Gene names (synonym ):Cyp2e Cyp2e-1
Gene names (ORF ):
Length:493
Mass:56805
Sequence:MAVLGITVALLVWIATLLLVSIWKQIYRSWNLPPGPFPIPFFGNIFQLDLKDIPKSLTKLAKRFGPVFTLHLGQRRIVVLHGYKAVKEVLLNHKNEFSGRGDIPVFQEYKNKGIIFNNGPTWKDVRRFSLSILRDWGMGKQGNEARIQREAHFLVEELKKTKGQPFDPTFLIGCAPCNVIADILFNKRFDYDDKKCLELMSLFNENFYLLSTPWIQAYNYFSDYLQYLPGSHRKVMKNVSEIRQYTLGKAKEHLKSLDINCPRDVTDCLLIEMEKEKHSQEPMYTMENISVTLADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRAPAVRDRMNMPYMDAVVHEIQRFINLVPSNLPHEATRDTVFRGYVIPKGTVVIPTLDSLLFDNYEFPDPETFKPEHFLNENGKFKYSDYFKAFSAGKRVCVGEGLARMELFLLLSAILQHFNLKSLVDPKDIDLSPVTIGFGSIPREFKLCVIPRS
Tissue specificity:Highest level in the liver and to a lesser extent in the kidney, with a higher level in the male kidney than in the female.
Induction:By ethanol and acetone in the liver and by testosterone in the kidney and adrenal tissues.
Developmental stage:Detectable in the female liver on day 1 and reaches steady state levels on days 16-20.
Protein families:Cytochrome P450 family