ABI1_MOUSE   Q8CBW3


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UniProt:Q8CBW3

Recommended name:Abl interactor 1

EC number:

Alternative names:(Abelson interactor 1) (Abi-1) (Ablphilin-1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Spectrin SH3 domain-binding protein 1) (e3B1)

Cleaved into:

GeneID:11308

Gene names  (primary ):Abi1

Gene names  (synonym ):Ssh3bp1

Gene names  (ORF ):

Length:481

Mass:52288

Sequence:MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQKPPSPPVSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTAGPAAPGAAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVAAQFSAQPHVNGGPLYSQNSISVAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYSDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEGVCNRVTGLFPGNYVESIMHYTD

Tissue specificity:Widely expressed with highest levels in bone marrow, spleen, brain, testes, and embryonic brain. In adult brain prominently expressed in the neocortex, hippocampus and dentate gyrus. {ECO:0000269|PubMed:10995551, ECO:0000269|PubMed:7590237}.

Induction:

Developmental stage:Detected at 10 dpc and 12 dpc in developing brain, but does not appear more prominent in the neuroepithelium compared to the surrounding tissue. {ECO:0000269|PubMed:10995551}.

Protein families:ABI family


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