ABI1_MOUSE Q8CBW3
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UniProt:Q8CBW3
Recommended name:Abl interactor 1
EC number:
Alternative names:(Abelson interactor 1) (Abi-1) (Ablphilin-1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Spectrin SH3 domain-binding protein 1) (e3B1)
Cleaved into:
GeneID:11308
Gene names (primary ):Abi1
Gene names (synonym ):Ssh3bp1
Gene names (ORF ):
Length:481
Mass:52288
Sequence:MAELQMLLEEEIPSGKRALIESYQNLTRVADYCENNYIQATDKRKALEETKAYTTQSLASVAYQINALANNVLQLLDIQASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANMERPVRYIRKPIDYTVLDDVGHGVKWLKAKHGNNQPARTGTLSRTNPPTQKPPSPPVSGRGTLGRNTPYKTLEPVKPPTVPNDYMTSPARLGSQHSPGRTASLNQRPRTHSGSSGGSGSRENSGSSSIGIPIAVPTPSPPTAGPAAPGAAPGSQYGTMTRQISRHNSTTSSTSSGGYRRTPSVAAQFSAQPHVNGGPLYSQNSISVAPPPPPMPQLTPQIPLTGFVARVQENIADSPTPPPPPPPDDIPMFDDSPPPPPPPPVDYEDEEAAVVQYSDPYADGDPAWAPKNYIEKVVAIYDYTKDKDDELSFKEGAIIYVIKKNDDGWFEGVCNRVTGLFPGNYVESIMHYTD
Tissue specificity:Widely expressed with highest levels in bone marrow, spleen, brain, testes, and embryonic brain. In adult brain prominently expressed in the neocortex, hippocampus and dentate gyrus. {ECO:0000269|PubMed:10995551, ECO:0000269|PubMed:7590237}.
Induction:
Developmental stage:Detected at 10 dpc and 12 dpc in developing brain, but does not appear more prominent in the neuroepithelium compared to the surrounding tissue. {ECO:0000269|PubMed:10995551}.
Protein families:ABI family