SOX18_MOUSE P43680
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UniProt:P43680
Recommended name:Transcription factor SOX-18
EC number:
Alternative names:
Cleaved into:
GeneID:20672
Gene names (primary ):Sox18
Gene names (synonym ):Sox-18
Gene names (ORF ):
Length:377
Mass:40898
Sequence:MQRSPPGYGAQDDPPSRRDCAWAPGIGAAAEARGLPVTNVSPTSPASPSSLPRSPPRSPESGRYGFGRGERQTADELRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNTAEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQARKVRRLEPGLLLPGLVQPSAPPEAFAAASGSARSFRELPTLGAEFDGLGLPTPERSPLDGLEPGEASFFPPPLAPEDCALRAFRAPYAPELARDPSFCYGAPLAEALRTAPPAAPLAGLYYGTLGTPGPFPNPLSPPPESPSLEGTEQLEPTADLWADVDLTEFDQYLNCSRTRPDATTLPYHVALAKLGPRAMSCPEESSLISALSDASSAVYYSACISG
Tissue specificity:Detected in adult lung, heart and skeletal muscles. {ECO:0000269|PubMed:7665083}.
Induction:
Developmental stage:Detected at 7.5 and 8.0 dpc in the allantois and blood islands of the yolk sac, and in cells fated to become the endocardium. At 8.5 dpc, detected in the allantois and the nascent vasculature of the yolk sac, the paired dorsal aortae and heart (PubMed:10742113). At 9.5 to 11.0 dpc, detected in endothelial cells of the paired dorsal aortae, in intersomitic vessels and in a network of smaller vessels in head and trunc mesenchyme, and in endothelial cells lining the dorsolateral sector of the cardinal vein (PubMed:10742113, PubMed:18931657). At 10.5 dpc, detected inprecursors of the lymphatic vasculature (PubMed:18931657). At 12.5 dpc, detected in branching vessels and in nascent vibrissae follicles. Detected in vibrissae follicles and pelage follicles at 14.0 dpc (PubMed:10742113). Detected in primary lymph sacs at 13.5 dpc, but is not detected in embryonic or adult lymph vessels (PubMed:18931657). {ECO:0000269|PubMed:10742113, ECO:0000269|PubMed:18931657}.
Protein families: