EGLN3_MOUSE Q91UZ4
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UniProt:Q91UZ4
Recommended name：Prolyl hydroxylase EGLN3
EC number：EC 1.14.11.-
Alternative names：(Egl nine homolog 3) (Hypoxia-inducible factor prolyl hydroxylase 3) (HIF-PH3) (HIF-prolyl hydroxylase 3) (HPH-3) (Prolyl hydroxylase domain-containing protein 3) (PHD3) (SM-20)
Cleaved into：
GeneID：112407
Gene names (primary )：Egln3
Gene names (synonym )：
Gene names (ORF )：
Length：239
Mass：27302
Sequence：MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHYNGALRDGQLAGPRAGVSKRHLRGDQITWIGGNEEGCEAINFLLSLIDRLVLYCGSRLGKYYVKERSKAMVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLHGGVLRIFPEGKSFVADVEPIFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALAKD
Tissue specificity：Highly expressed in cardiac and smooth muscle. Also high expression in brain, skeletal muscle and kidney. Low levels in lung. {ECO:0000269|PubMed:12234095}.
Induction：Induced by hypoxia. Up-regulated in proliferating myoblasts induced to form differentiated myotubes. {ECO:0000269|PubMed:21317538}.
Developmental stage：Detected at 8.5 dpc in proliferating myoblasts of the dermomyotome and the developing heart tube. From dermomyotomal cells of the rostral somites expression progressed in a rostral to caudal pattern, with highest levels seen in the muscle primordia and mature muscles. {ECO:0000269|PubMed:10543731}.
Protein families：