FLRT1_MOUSE Q6RKD8
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UniProt:Q6RKD8
Recommended name:Leucine-rich repeat transmembrane protein FLRT1
EC number:
Alternative names:(Fibronectin leucine rich transmembrane protein 1)
Cleaved into:
GeneID:396184
Gene names (primary ):Flrt1
Gene names (synonym ):
Gene names (ORF ):
Length:646
Mass:71492
Sequence:MDLRDWLFLCYGLIAFLTEVIDSTTCPSVCRCDNGFIYCNDRGLTSIPSDIPDDATTLYLQNNQINNAGIPQDLKTKVKVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDLSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVRARAAVVNVRGLMCQGPEKVRGMAIKDITSEMDECFEAGSQGGAANAAAKTTVSNHASATTPQGSLFTLKAKRPGLRLPDSNIDYPMATGDGAKTLVIQVKPLTADSIRITWKAMLPASSFRLSWLRLGHSPAVGSITETLVQGDKTEYLLTALEPKSTYIICMVTMETGNTYVADETPVCAKAETADSYGPTTTLNQEQNAGPMAGLPLAGIIGGAVALVFLFLVLGAICWYVHRAGELLTRERVYNRGSRRKDDYMESGTKKDNSILEIRGPGLQMLPINPYRSKEEYVVHTIFPSNGSSLCKGAHTIGYGTTRGYREAGIPDVDYSYT
Tissue specificity:Detected in brain (at protein level). {ECO:0000269|PubMed:21673655}.
Induction:Up-regulated by FGF2. {ECO:0000269|PubMed:16872596}.
Developmental stage:Detected at comparable levels in embryonic brain and in brain from ten day old animals (at protein level) (PubMed:16872596). Detected in neuroectoderm at 7.5 dpc. Detected in midbrain between 8.5 and 9 dpc (PubMed:18448090). Detected at 9.5 dpc in embryonic midbrain adjacent to the boundary between midbrain and forebrain (PubMed:16872596). At 10.5 dpc, expression is also detected in the eye, throughout the brain, the dorsal root ganglia and trigeminal ganglia, and in cells adjacent to the urogenital ridge in the torso (PubMed:16872596, PubMed:18448090). At 11 dpc, expression in midbrain is tightly restricted to the boundary between midbrain and hindbrain (PubMed:16872596). {ECO:0000269|PubMed:16872596}.
Protein families: