CAT8_MOUSE Q9JI81
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UniProt:Q9JI81
Recommended name：Cathepsin 8
EC number：EC 3.4.22.-
Alternative names：(Cathepsin 2)
Cleaved into：
GeneID：56094
Gene names (primary )：Cts8
Gene names (synonym )：Cts2 Epcs68 Epcs70
Gene names (ORF )：
Length：333
Mass：37803
Sequence：MGPAVLLAILCLGVAEVTQSSDPSLDSEWQEWKRKFNKNYSMEEEGQKRAVWEENMKLVKQHNIEYDQGKKNFTMDVNAFGDMTGEEYRKMLTDIPVPNFRKKKSIHQPIAGYLPKFVDWRKRGCVTPVKNQGTCNSCWAFSAAGAIEGQMFRKTGKLVPLSTQNLVDCSRLEGNFGCFKGSTFLALKYVWKNRGLEAESTYPYKGTDGHCRYHPERSAARITSFSFVSNSEKDLMRAVATIGPISVGIDARHKSFRLYREGIYYEPKCSSNIINHSVLVVGYGYEGKESDGNKYWLIKNSHGEQWGMNGYMKLARGRNNHCGIASYAVYPRV
Tissue specificity：Expressed in placenta (PubMed:11829493, PubMed:10885754, PubMed:18776147). Highly expressed in a subset of trophoblast giant cells in the parietal yolk sac and at the outside of the ectoplacental cone (PubMed:10885754). Expressed at highest level in liver with lesser amounts in testis, kidney, heart, lung and brain (PubMed:10885754). Not detected in spleen and skeletal muscle (PubMed:10885754, PubMed:11829493). Not detected in blood, heart, brain, testis, liver, lung, kidney, thymus or uterus (PubMed:11829493). {ECO:0000269|PubMed:10885754, ECO:0000269|PubMed:11829493, ECO:0000269|PubMed:18776147}.
Induction：
Developmental stage：Detected from 5.5 dpc in parietal trophoblast giant cells (PubMed:18776147, PubMed:10885754). Detected at 8.5 dpc in placenta, and shows increased expression level from 13.5 to 19.5 dpc (PubMed:11829493). {ECO:0000269|PubMed:10885754, ECO:0000269|PubMed:11829493, ECO:0000269|PubMed:18776147}.
Protein families：Peptidase C1 family