DMBX1_MOUSE Q91ZK4
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UniProt:Q91ZK4
Recommended name:Diencephalon/mesencephalon homeobox protein 1
EC number:
Alternative names:(Diencephalon/mesencephalon-expressed brain homeobox gene 1 protein) (Orthodenticle homolog 3) (Paired-like homeobox protein DMBX1) (Paired-type homeobox Atx)
Cleaved into:
GeneID:140477
Gene names (primary ):Dmbx1
Gene names (synonym ):Cdmx Mbx Otx3 PaxB
Gene names (ORF ):
Length:381
Mass:41115
Sequence:MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKVEAPASDTQLETEQPPGLPSGDPPAELQLSLSEQSASESAPEDQLDREEDSRAEEPKAEKSPGSESKVPGCKRGSPKADSPGSLAITPAAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLMHYSSFEVGGPAPAAAAAAAAAVPYLGVNMAPLSSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPTGLAPASAALNSKTTSIENLRLRAKQHAASLGLDTLPN
Tissue specificity:Expressed in adult brain, stomach, and testis. Expressed in the developing diencephalon, midbrain and hindbrain. During limb development, expressed in a temporal pattern with expression being first restricted to the forelimbs and then subsequently to the hindlimbs. {ECO:0000269|PubMed:11744391, ECO:0000269|PubMed:11914943, ECO:0000269|PubMed:12111214, ECO:0000269|PubMed:12175514}.
Induction:
Developmental stage:Detected in embryo from 10.5 to 13.5 dpc. Strongly expressed from 9.5 to 11.5 dpc in the diencephalon, mesencephalon, metencephalon, myeloencephalon, and the developing eye. {ECO:0000269|PubMed:11744391, ECO:0000269|PubMed:12055180, ECO:0000269|PubMed:12175515}.
Protein families:Paired homeobox family