OAS1D_MOUSE Q8VI95
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UniProt:Q8VI95
Recommended name：Inactive 2'-5'-oligoadenylate synthase 1D
EC number：
Alternative names：
Cleaved into：
GeneID：100535
Gene names (primary )：Oas1d
Gene names (synonym )：Oasl8
Gene names (ORF )：
Length：361
Mass：42831
Sequence：MARELFRTPIWRLDKFIEDQLLPDTTFLTELRADIDSISAFLMERCFQGAAHPVRVSRVVMGGCYNEYTVLKGRSEANMVVFLINLTSFEDQFNGQVVFIEEIWRHLLQLQQEKLCKLKFEVQSPKEPNSRFLSFKLSCPERQHELEFDVQPAYDALYEVRHFKPFDSSNYNKVYAQLTHECTTLEKEGEFSICFTDLHQSFLRYRAPKLWNLIRLVKHWYQLCKEKLRGPLPPQYALELLTVYVWEYGIHENPGLHTAQCFRTVLELVTKYKRLRIYWTWCYDFQHEISDYLQGQIKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQIWIDSTFFTNHDMSIVEAWEVMPERQECVFL
Tissue specificity：Expressed specifically in oocytes (at protein level) (PubMed:15899864). Expressed at highest level in ovary with lesser amounts in intestine, brain, thymus lung, kidney, liver and uterus (PubMed:17567914, PubMed:27663720). {ECO:0000269|PubMed:15899864, ECO:0000269|PubMed:17567914, ECO:0000269|PubMed:27663720}.
Induction：Unlike other OAS1 proteins, not induced by polyinosinic:polycytidylic acid (poly I:C). {ECO:0000269|PubMed:15899864, ECO:0000269|PubMed:27663720}.
Developmental stage：Detected in fully grown, germinal vesicle (GV)-intact oocytes and in oocytes at the metaphase II stage, with levels decreasing thereafter (at protein level) (PubMed:15899864). Detected 1 week after birth in developing ovary (PubMed:27663720). Detected at 17.5 dpc, with levels increasing thereafter (PubMed:17567914). {ECO:0000269|PubMed:15899864, ECO:0000269|PubMed:17567914, ECO:0000269|PubMed:27663720}.
Protein families：2-5A synthase family