RFX2_MOUSE P48379
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UniProt:P48379
Recommended name：DNA-binding protein RFX2
EC number：
Alternative names：(Regulatory factor X 2)
Cleaved into：
GeneID：19725
Gene names (primary )：Rfx2
Gene names (synonym )：
Gene names (ORF )：
Length：717
Mass：79190
Sequence：MQNSEGGADSPASVALRPAAQPMPASPQRVLVQAAGSTPKGTPMQTLTLPRVQPVPPQVQHVYPAQVQYVEGGDAVYANGAIRAAYAYNPDPQLYAPSSAASYFETPGGTQVTVAASSPPAVPSHGMVGITMDVSGTPIVSGAGAYLIHGGMDGTRHSLAHTARSSPATLEMAIETLQKSEGLAPHKGGLLNSHLQWLLDNYETAEGVSLPRSSLYNHYLRHCQEHKLEPVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGIRLKPDSPLNRLQEDTQYMAMRQQPTHQKPRYRPAQKSDSLGDGSAHSNMHGMPDQAMATQGQHHQQYIDVSHVFPEFPAPDLGSTLLQESVTLHDVKALQLVYRRHCEATLDVVMNLQFQYIEKLWLSFWNCKATSSDSCASLPASDEDPEVTLLPKEKLISLCKCEPILQWMRSCDHILYQTLVETLIPDVLRPVPSSLTQAIRNFAKSLEGWLINAMSGFPQQVIQTKVGVVSAFAQTLRRYTSLNHLAQAARAVLQNTSQINQMLSDLNRVDFANVQEQASWVCQCEESLVQRLEHDFKVTLQQQSSLDQWASWLDNVVTQVLKQHSGSPSFPKAARQFLLKWSFYSSMVIRDLTLRSAASFGSFHLIRLLYDEYMFYLVEHRVAQATGETPIAVMGEFNDLASLSLTLLDKEDIGDGHSSEADVDGRSLGEPLVKRERSDPSHPLQGI
Tissue specificity：
Induction：
Developmental stage：Detected in the anterior primitive streak preceding the morphological appearance of the node at 7.0 dpc. Expressed in the node and in the midline notochordal plate cells extending anteriorly from the node at 7.5 dpc. At 8.5 dpc, expressed in the node now located in the tail region. At 9.5 dpc, detected in the floor plate and in the dorsal portion of the neural tube, with highest expression in the anterior portion of the spinal cord. Also expressed in the developing gut. At 10.5 dpc, also observed in the telencephalon region of the brain and in the anterior portion of the limb bud at 12.5 dpc (PubMed:26248850). Localizes to cells at the posterior margin of the ciliated organ of asymmetry (PubMed:22233545). {ECO:0000269|PubMed:22233545, ECO:0000269|PubMed:26248850}.
Protein families：RFX family