OSBL6_MOUSE Q8BXR9
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UniProt:Q8BXR9
Recommended name：Oxysterol-binding protein-related protein 6
EC number：
Alternative names：(ORP-6) (OSBP-related protein 6)
Cleaved into：
GeneID：99031
Gene names (primary )：Osbpl6
Gene names (synonym )：
Gene names (ORF )：
Length：959
Mass：108920
Sequence：MSSDEKGISPAHKTSTPTHRSASSSTSSQRESRQSIHVLERTASSSTEPSVSRQLLEPEPIPLSKEADSWEIIEGLKIGQTNVQKPDRHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPATSTAESSPAANVSVVDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQEGPPAKGQFNTTRRRQRLAAAVATTVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQVVSEQDHNKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESTICDHVVSVNIIPSPDEPGEQIHVSLPLSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRTCLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVTLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTLRNTKSSVCICKLTFVKVNYWNSNVNEVQGVVIDQEGKVVHRLFGKWHEGLYCGVAPSAKCIWRPGSLPTNYELYYGFTRFAVELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAAAEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW
Tissue specificity：Expressed in skin, respiratory epithelium, small intestine epithelium, pancreas, striated muscle, brain, spinal ganglia, and nervous plexus of the intestine (at protein level) (PubMed:14593528, PubMed:30028970). In the brain, specifically in the cerebellum, it is expressed in Purkinje and granule cells (PubMed:30028970). Expressed in hepatocytes and macrophages (PubMed:26941018). {ECO:0000269|PubMed:14593528, ECO:0000269|PubMed:26941018, ECO:0000269|PubMed:30028970}.
Induction：By acetylated low-density lipoprotein and dietary intake of cholesterols. {ECO:0000269|PubMed:26941018}.
Developmental stage：Detected in the brain at 18.5 days post coitum (dpc), with expression increasing till it reaches its peak expression at 28 dpc. {ECO:0000269|PubMed:30028970}.
Protein families：OSBP family