NTNG1_MOUSE Q8R4G0
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UniProt:Q8R4G0
Recommended name：Netrin-G1
EC number：
Alternative names：(Laminet-1)
Cleaved into：
GeneID：80883
Gene names (primary )：Ntng1
Gene names (synonym )：Kiaa0976 Lmnt1
Gene names (ORF )：
Length：539
Mass：60566
Sequence：MYLSRFLSIHALWVTVSSVMQPYLFVWGHYDVCKSLIYTEEGKVWDYTACQPESTDMTKYLKVKLDPPDITCGDPPESFCAMGNPYMCNNECDASTPELAHPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQMILEKSLDYGRTWQPYQYYATDCLHAFHMDPKSVKDLSQHTVLEIICTEEYSTGYSTNSKIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLRPAVGEIFVDELHLARYFYAISDIKVRGRCKCNLHATSCLYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNGSGFCECKTGTTGPKCDECLPGNSWYYGCQPNVCDNELLHCQNGGTCQNNVRCACPDAYTGILCEKLRCEEAGSCGSESGQGAPPRGSPALLLLTMLLGTAGPLVF
Tissue specificity：Expression is restricted primarily to neurons of the CNS, particularly in the dorsal thalamus, olfactory bulb and inferior colliculus. Isoform 1A and isoform 1D are the major products in adult brain. {ECO:0000269|PubMed:10964959, ECO:0000269|PubMed:11804778, ECO:0000269|PubMed:11906208}.
Induction：
Developmental stage：Detected in the midbrain and the hindbrain regions as early as 12 dpc. In the deep nucleus of the cerebellum, as well as in the inferior colliculus and the thalamic regions, expression is detected at 14 dpc, persists to postnatal day 1 and is down-regulated by postnatal day 12. At 14 dpc, expression is segmented in dorsal thalamus and pretectum in the midbrain and is regulated in a layer-specific manner in the superior colliculus. In the olfactory bulb, expression is detected at 14 dpc, increases by postnatal day 1 and is maintained at a high level through postnatal day 21 and into adulthood. {ECO:0000269|PubMed:10964959}.
Protein families：