SG3A2_MOUSE   Q920H1


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UniProt:Q920H1

Recommended name:Secretoglobin family 3A member 2

EC number:

Alternative names:(Pneumo secretory protein 1) (PnSP-1) (Uteroglobin-related protein 1)

Cleaved into:

GeneID:117158

Gene names  (primary ):Scgb3a2

Gene names  (synonym ):Pnsp1 Ugrp1

Gene names  (ORF ):

Length:91

Mass:9819

Sequence:MKLVSIFLLVTIGICGYSATALLINRLPVVDKLPVPLDDIIPSFDPLKMLLKTLGISVEHLVTGLKKCVDELGPEASEAVKKLLEALSHLV

Tissue specificity:Highly expressed in lung where it localizes to epithelial cells of the trachea, bronchus and bronchioles (at protein level) (PubMed:11682631, PubMed:12406855, PubMed:12175512, PubMed:25242865). Expressed in club/Clara cells of the bronchioles (PubMed:12406855). Also detected in the anterior and posterior lobes of the pituitary gland where it may localize to gonadotropic cells (at protein level) (PubMed:24514953). Not detected in other tissues tested (PubMed:11682631, PubMed:12175512). {ECO:0000269|PubMed:11682631, ECO:0000269|PubMed:12175512, ECO:0000269|PubMed:12406855, ECO:0000269|PubMed:24514953, ECO:0000269|PubMed:25242865}.

Induction:

Developmental stage:Detected in the pituitary gland from postnatal day 1 onwards (at protein level) (PubMed:24514953). Weakly expressed in embryonic lung at stages 11.5 dpc and 12.5 dpc (PubMed:11682631, PubMed:18535256). Seems to localize most strongly to the growing tips of bronchi at stage 13.5 dpc (PubMed:18535256). Highly expressed in developing lung at stages 16.5 dpc and 18.5 dpc, where it localizes to airway epithelia (PubMed:11682631, PubMed:12406855, PubMed:12175512, PubMed:24514953). During gestation, detected in the mammary gland at 6.5 days post coitum (dpc), but expression declines at 8.5 dpc and is absent at later stages (PubMed:12175512). {ECO:0000269|PubMed:11682631, ECO:0000269|PubMed:12175512, ECO:0000269|PubMed:12406855, ECO:0000269|PubMed:18535256, ECO:0000269|PubMed:24514953}.

Protein families:Secretoglobin family, UGRP subfamily


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