MEIOB_MOUSE   Q9D513


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UniProt:Q9D513

Recommended name:Meiosis-specific with OB domain-containing protein

EC number:EC 3.1.-.-

Alternative names:(Protein expressed in male leptotene and zygotene spermatocytes 675) (MLZ-675)

Cleaved into:

GeneID:75178

Gene names  (primary ):Meiob

Gene names  (synonym ):

Gene names  (ORF ):

Length:470

Mass:52975

Sequence:MAKFFALKNFTALSDLHPNMANLKIIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSPCHFVNVSSWGSEDYIRSLSESFRVAECVIIENPLIQRKDTEREEKFSPATPSNYKLLLSENHSMVKVCSPYEVDTKLLSLIHLPVKESRDYYSLADIVANGHSLDGRIINVLAAVRSVGEPKYFTTSDRRKGQRCEVKLFDETEPSFTMTCWDNESILLAQSWMARETVIFASDVRINFNKFQNCMAATVISKTIITVNPDTPEANILLNYIRENKETNVADEIDSYLKESVNLNTIVDVYTVEQLKVKALKSEGKADPFYGILYAYISTLNIDDETTKVVRNRCSSCGYIVNEASNTCTICNQDSSRLKSFFLSFDVLVDLTDHTGTLHSCSLSGSIAEETLGCTINEFLTMTSEQKTKLKWQLLLERSKIYLKLILSHRARGGLKVTILSCKLADPTEASRNLARQGHT

Tissue specificity:Sprecifically expressed in early meiotic germ cells: in adult and fetal tissues, detected in fetal ovary, postnatal testis and liver. In the ovary, expression starts at 12.5 dpc, reaches a maximum at 15.5 dpc and decreases to become undetectable in post natal life. In testis, expression starts at 10 days post partum (dpp), reaches a maximum at 20 dpp and is maintained throughout adult life. {ECO:0000269|PubMed:24068956, ECO:0000269|PubMed:24240703}.

Induction:

Developmental stage:Detected only during early meiosis prophase I (early 4N-fraction containing leptotene, zygotene and few pachytenes spermatocytes) and not during later stages of meiosis (at protein level). {ECO:0000269|PubMed:24068956, ECO:0000269|PubMed:24240703}.

Protein families:MEIOB family


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