WEE2_MOUSE Q66JT0
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UniProt:Q66JT0
Recommended name:Wee1-like protein kinase 2
EC number:EC 2.7.10.2
Alternative names:(Wee1-like protein kinase 1B) (Wee1B kinase) (mWee1B)
Cleaved into:
GeneID:381759
Gene names (primary ):Wee2
Gene names (synonym ):Wee1b
Gene names (ORF ):
Length:555
Mass:62343
Sequence:MADTETDQGLNKKLSFSFCEEDTESEGQMTAQDIGGAQSQKPGREESEELEGPVPPTRDELHTSLSRDKESPGPDLWKSVSGPPKCPETPVLHSKSKLPVPTNFSTPKNSLGQPEISLLEKLSSRSSRHMRLTPASLMDEKTSLSLVNINPFTPETYRKLLLQSKGKRKTRDYLEETGEEESKSVQWLPAKRSILQETNMASRYEKEFFEIEKIGVGEFGTVYKCIKRLDGCIYAIKRSAKSFSGLSNELDLHEVYAHAVLGHHPHVVRYYSSWIEDDHVVIQNEYCNGGSLQAAISENTASNNHFQEPKLKDILLQISLGLKYIHNSGMVHLDIKPSNIFICHKMQCDSPVGPEEAESEADWFLNASVMYKIGDLGHATSISKPKVEEGDTRFLANEILQENYQHLPKADIFALGLTIAVAAGAESLPINGDMWHHIRKGNFPEISQELSDDFYGLLKNMIHPAPKERPSAAALARSRILWPFLEKTDELQKQLNLEKSKTATLKRELKKARHIQTPQREVHHCYYQICKGSRHLLVGGRRKAPSSFTRGTSSV
Tissue specificity:Ovary-specific. {ECO:0000269|PubMed:16169490}.
Induction:
Developmental stage:Detected only in the oocytes at all developmental stages of the follicle including primary, secondary, preantral, and antral follicles with an increase in signal during development. Readily detectable at the mature oocyte, but disappears at 2.5 dpc. Detected in germinal vesicle (GV) and metaphase II-stage oocyte (at protein level). {ECO:0000269|PubMed:16169490, ECO:0000269|PubMed:21454751}.
Protein families:Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily