S22A6_MOUSE   Q8VC69


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UniProt:Q8VC69

Recommended name:Solute carrier family 22 member 6

EC number:

Alternative names:(Kidney-specific transport protein) (Novel kidney transcript) (mNKT) (Organic anion transporter 1) (Renal organic anion transporter 1) (mROAT1)

Cleaved into:

GeneID:18399

Gene names  (primary ):Slc22a6

Gene names  (synonym ):Nkt Oat1

Gene names  (ORF ):

Length:545

Mass:60013

Sequence:MAFNDLLKQVGGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPAHHCRPPANANLSKDGGLEAWLPLDKQGRPESCLRFPFPHNGTEANGTGVTEPCLDGWVYDNSTFPSTIVTEWNLVCSHRAFRQLAQSLFMVGVLLGAMMFGYLADRLGRRKVLILNYLQTAVSGTCAAYAPNYTVYCIFRLLSGMSLASIAINCMTLNMEWMPIHTRAYVGTLIGYVYSLGQFLLAGIAYAVPHWRHLQLAVSVPFFVAFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQEEGAKLSIEVLQTSLQKELTLNKGQASAMELLRCPTLRRLFLCLSMLWFATSFAYYGLVMDLQGFGVSMYLIQVIFGAVDLPAKFVCFLVINSMGRRPAQLASLLLAGICILVNGIIPRGHTIIRTSLAVLGKGCLASSFNCIFLYTGELYPTMIRQTGLGMGSTMARVGSIVSPLISMTAEFYPSIPLFIFGAVPVAASAVTALLPETLGQPLPDTVQDLKSRSRGKQKQQQLEQQKQMIPLQVSTQEKNGL

Tissue specificity:Expressed in kidney; in the basolateral membrane and at much lower levels in brain. {ECO:0000269|PubMed:9045672, ECO:0000269|PubMed:9880528}.

Induction:

Developmental stage:Developmentally regulated with significant expression beginning at 18 dpc and rising just before birth.

Protein families:Major facilitator (TC 2.A.1) superfamily, Organic cation transporter (TC 2.A.1.19) family


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