PO5F1_MOUSE P20263
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UniProt:P20263
Recommended name：POU domain, class 5, transcription factor 1
EC number：
Alternative names：(NF-A3) (Octamer-binding protein 3) (Oct-3) (Octamer-binding protein 4) (Oct-4) (Octamer-binding transcription factor 3) (OTF-3)
Cleaved into：
GeneID：18999
Gene names (primary )：Pou5f1
Gene names (synonym )：Oct-3 Oct-4 Otf-3 Otf3
Gene names (ORF )：
Length：352
Mass：38216
Sequence：MAGHLASDFAFSPPPGGGDGSAGLEPGWVDPRTWLSFQGPPGGPGIGPGSEVLGISPCPPAYEFCGGMAYCGPQVGLGLVPQVGVETLQPEGQAGARVESNSEGTSSEPCADRPNAVKLEKVEPTPEESQDMKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSLKNMCKLRPLLEKWVEEADNNENLQEICKSETLVQARKRKRTSIENRVRWSLETMFLKCPKPSLQQITHIANQLGLEKDVVRVWFCNRRQKGKRSSIEYSQREEYEATGTPFPGGAVSFPLPPGPHFGTPGYGSPHFTTLYSVPFPEGEAFPSVPVTALGSPMHSN
Tissue specificity：Expressed the totipotent and pluripotent stem cells of the pregastrulation embryo. Also expressed in primordial germ cells and in the female germ line. Absent from adult tissues. {ECO:0000269|PubMed:1690859, ECO:0000269|PubMed:1972777}.
Induction：Repressed by retinoic acid (RA). {ECO:0000269|PubMed:1690859, ECO:0000269|PubMed:1915274, ECO:0000269|PubMed:1967980}.
Developmental stage：Down-regulated during differentiation to endoderm and mesoderm. {ECO:0000269|PubMed:1972777}.
Protein families：POU transcription factor family, Class-5 subfamily