BMP10_MOUSE Q9R229
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UniProt:Q9R229
Recommended name：Bone morphogenetic protein 10
EC number：
Alternative names：(BMP-10)
Cleaved into：
GeneID：12154
Gene names (primary )：Bmp10
Gene names (synonym )：
Gene names (ORF )：
Length：421
Mass：47888
Sequence：MGSLVLPLSAVFCLVAHSASGSPIMGLEQSPLEEDMPFFDDIFTEQDGIDFNTLLQSMKNEFLKTLNLSDIPVQDTGRVDPPEYMLELYNKFATDRTSMPSANIIRSFKNEDLFSQPVTFNGLRKYPLLFNVSIPHHEEVVMAELRLYTLVQRDRMMYDGVDRKITIFEVLESADGSEEERSMLVLVSTEIYGTNSEWETFDVTDATRRWQKSGPSTHQLEIHIESRQNQAEDTGRGQLEIDMSAQNKHDPLLVVFSDDQSNDKEQKEELNELITHEQDLDLDSDAFFSGPDEEALLQMRSNMIDDSSARIRRNAKGNYCKKTPLYIDFKEIGWDSWIIAPPGYEAYECRGVCNYPLAEHLTPTKHAIIQALVHLKNSQKASKACCVPTKLDPISILYLDKGVVTYKFKYEGMAVSECGCR
Tissue specificity：In the embryo, expressed exclusively in the ventricular trabecular myocardium of the developing heart from 9.0 dpc-13.5 dpc. By 16.5 dpc-18.5 dpc, only detectable in atria. Highly expressed in the adult heart where it is found in the right atrium but not in the left atrium. Lower levels in adult liver and lung. {ECO:0000269|PubMed:10072785, ECO:0000269|PubMed:15073151, ECO:0000269|PubMed:15109497}.
Induction：
Developmental stage：Down-regulation after 14.5 dpc is critical for cardiomyocytes to undergo normal developmental hypertrophic growth in early postnatal life. {ECO:0000269|PubMed:16798733}.
Protein families：TGF-beta family