NP1L1_MOUSE P28656
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UniProt:P28656
Recommended name:Nucleosome assembly protein 1-like 1
EC number:
Alternative names:(Brain protein DN38) (NAP-1-related protein)
Cleaved into:
GeneID:53605
Gene names (primary ):Nap1l1
Gene names (synonym ):Nrp
Gene names (ORF ):
Length:391
Mass:45345
Sequence:MADIDNKEQSELDQDLEDVEEVEEEETGEETKIKARQLTVQMMQNPQILAALQERLDGLVDTPTGYIESLPKVVKRRVNALKNLQVKCAQIEAKFYEEVHDLERKYAVLYQPLFDKRFEIINAIYEPTEEECEWKPDEEDEVSEELKEKAKIEDEKKDEEKEDPKGIPEFWLTVFKNVDLLSDMVQEHDEPILKHLKDIKVKFSDAGQPMSFVLEFHFEPNDYFTNEVLTKTYRMRSEPDDSDPFSFDGPEIMGCTGCQIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVSNDSFFNFFAPPEVPENGDLDDDAEAILAADFEIGHFLRERIIPRSVLYFTGEAIEDDDDDYDEEGEEADEEGEEEGDEENDPDYDPKKDQNPAECKQQ
Tissue specificity:Highly expressed in the brain (at protein level) (PubMed:29490266). High expression in cerebral cortex, not in cerebellar cortex. {ECO:0000269|PubMed:29490266}.
Induction:
Developmental stage:During brain development, expression decreases from 12 dpc to P0. Expressed predominantly but not restricted in the ventricular zone (VZ)/subventricular zone (SVZ), and peak expression is observed at 12.5 dpc, in which the cerebral cortex consists primarily of neural progenitor cells (NPCs). At 15.5 dpc, the expression decreases in the cerebral cortical plate. At 18.5 dpc, when the embryonic neurogenesis period nears its end, the expression throughout the cerebral cortex is lower than that at 12.5 dpc (at protein level). {ECO:0000269|PubMed:29490266}.
Protein families:Nucleosome assembly protein (NAP) family