ICMT_MOUSE Q9EQK7
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UniProt:Q9EQK7
Recommended name:Protein-S-isoprenylcysteine O-methyltransferase
EC number:EC 2.1.1.100
Alternative names:(Isoprenylcysteine carboxylmethyltransferase) (Prenylated protein carboxyl methyltransferase) (PPMT) (Prenylcysteine carboxyl methyltransferase) (pcCMT)
Cleaved into:
GeneID:57295
Gene names (primary ):Icmt
Gene names (synonym ):
Gene names (ORF ):
Length:283
Mass:31790
Sequence:MAAARRGSAGSEARLSLATFLLGASVLALPLLTRAGLQGRTGLALYVAGLNALLLLLYRPPRYQIAIRACFLGFVFGCGVLLSFSQSSWNHFGWYVCSLSLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWIEFTLENIFWPELKQITWLSATGLLMVVFGECLRKAAMFTAGSNFNHVVQSEKSDTHTLVTSGVYAWCRHPSYVGWFYWSIGTQVMLCNPICGVVYALTVWRFFRDRTEEEEISLIHFFGEEYLDYKKRVPTGLPFIKGVKVEL
Tissue specificity:Highly enriched in adult cerebellum, with a low level expression in other brain regions.
Induction:
Developmental stage:During cerebellar development expression was low before postnatal day P6 and dramatically increased after P12.
Protein families:Class VI-like SAM-binding methyltransferase superfamily, Isoprenylcysteine carboxyl methyltransferase family