ICMT_MOUSE   Q9EQK7


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UniProt:Q9EQK7

Recommended name:Protein-S-isoprenylcysteine O-methyltransferase

EC number:EC 2.1.1.100

Alternative names:(Isoprenylcysteine carboxylmethyltransferase) (Prenylated protein carboxyl methyltransferase) (PPMT) (Prenylcysteine carboxyl methyltransferase) (pcCMT)

Cleaved into:

GeneID:57295

Gene names  (primary ):Icmt

Gene names  (synonym ):

Gene names  (ORF ):

Length:283

Mass:31790

Sequence:MAAARRGSAGSEARLSLATFLLGASVLALPLLTRAGLQGRTGLALYVAGLNALLLLLYRPPRYQIAIRACFLGFVFGCGVLLSFSQSSWNHFGWYVCSLSLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWIEFTLENIFWPELKQITWLSATGLLMVVFGECLRKAAMFTAGSNFNHVVQSEKSDTHTLVTSGVYAWCRHPSYVGWFYWSIGTQVMLCNPICGVVYALTVWRFFRDRTEEEEISLIHFFGEEYLDYKKRVPTGLPFIKGVKVEL

Tissue specificity:Highly enriched in adult cerebellum, with a low level expression in other brain regions.

Induction:

Developmental stage:During cerebellar development expression was low before postnatal day P6 and dramatically increased after P12.

Protein families:Class VI-like SAM-binding methyltransferase superfamily, Isoprenylcysteine carboxyl methyltransferase family


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