SOCS5_MOUSE O54928
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UniProt:O54928
Recommended name:Suppressor of cytokine signaling 5
EC number:
Alternative names:(SOCS-5) (Cytokine-inducible SH2-containing protein 5)
Cleaved into:
GeneID:56468
Gene names (primary ):Socs5
Gene names (synonym ):Cish5
Gene names (ORF ):
Length:536
Mass:61086
Sequence:MDKVGKMWNNLKYRCQNLFSHEGGSRNENVEMNPNRCPSVKEKSISLGEAAPQQESSPLRENVALQLGLSPSKTFSRRNQNCAAEIPQVVEISIEKDSDSGATPGTRLARRDSYSRHAPWGGKKKHSCSTKTQSSLDTEKKFGRTRSGLQRRERRYGVSSMQDMDSVSSRAVGSRSLRQRLQDTVGLCFPMRTYSKQSKPLFSNKRKIHLSELMLEKCPFPAGSDLAQKWHLIKQHTAPVSPHSTFFDTFDPSLVSTEDEEDRLRERRRLSIEEGVDPPPNAQIHTFEATAQVNPLYKLGPKLAPGMTEISGDGSAIPQTNCDSEEDSTTLCLQSRRQKQRQVSGDSHAHVSRQGAWKVHTQIDYIHCLVPDLLQITGNPCYWGVMDRYEAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYNRSLHARIEQWNHNFSFDAHDPCVFHSSTVTGLLEHYKDPSSCMFFEPLLTISLNRTFPFSLQYICRAVICRCTTYDGIDGLPLPSMLQDFLKEYHYKQKVRVRWLEREPVKAK
Tissue specificity:Widely expressed. Expressed in TH1 but not TH2 cells. {ECO:0000269|PubMed:12242343}.
Induction:By a subset of cytokines including IL6 and LIF.
Developmental stage:During embryonic development, expressed from mid-to-late gestation and in yolk sac.
Protein families: