RSPH1_MOUSE   Q8VIG3


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UniProt:Q8VIG3

Recommended name:Radial spoke head 1 homolog

EC number:

Alternative names:(Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein)

Cleaved into:

GeneID:22092

Gene names  (primary ):Rsph1

Gene names  (synonym ):Tsga2

Gene names  (ORF ):

Length:301

Mass:34181

Sequence:MSDLGSEELEEEGENDLGEYEGERNEVGERHGHGKARLPNGDTYEGSYEFGKRHGQGTYKFKNGARYTGDYVKNKKHGQGTFIYPDGSRYEGEWADDQRHGQGVYYYVNNDTYTGEWFNHQRHGQGTYLYAETGSKYVGTWVHGQQEGAAELIHLNHRYQGKFMNKNPVGPGKYVFDIGCEQHGEYRLTDTERGEEEEEEETLVNIVPKWKALNITELALWTPTLSEEQPPPEGQGQEEPQGLTGVGDPSEDIQAEGFEGELEPRGADEDVDTFRQESQENSYDIDQGNLNFDEEPSDLQD

Tissue specificity:Expressed in the trachea, ependymal cells and oviduct (at protein level) (PubMed:32203505). Germ cell specific. Specifically expressed in testis, and to a lower extent in ovary. Not expressed in somatic tissues (PubMed:9578619). {ECO:0000269|PubMed:32203505, ECO:0000269|PubMed:9578619}.

Induction:

Developmental stage:During male germ cell development it is not detected until 12 days. Significant expression is detected from 14-day-old through to adult testis. Expression is first detected in the pachytene spermatocytes at stage V, becomes stronger from the late pachytene spermatocytes to round spermatid stage, and then gradually decreases as the morphogenesis proceeds further. Not expressed in germ cells located in the first layer of the seminiferous epithelium (spermatogonia, leptotene and zygotene spermatocytes). {ECO:0000269|PubMed:9578619}.

Protein families:


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