RSPH1_MOUSE Q8VIG3
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UniProt:Q8VIG3
Recommended name:Radial spoke head 1 homolog
EC number:
Alternative names:(Male meiotic metaphase chromosome-associated acidic protein) (Meichroacidin) (Testis-specific gene A2 protein)
Cleaved into:
GeneID:22092
Gene names (primary ):Rsph1
Gene names (synonym ):Tsga2
Gene names (ORF ):
Length:301
Mass:34181
Sequence:MSDLGSEELEEEGENDLGEYEGERNEVGERHGHGKARLPNGDTYEGSYEFGKRHGQGTYKFKNGARYTGDYVKNKKHGQGTFIYPDGSRYEGEWADDQRHGQGVYYYVNNDTYTGEWFNHQRHGQGTYLYAETGSKYVGTWVHGQQEGAAELIHLNHRYQGKFMNKNPVGPGKYVFDIGCEQHGEYRLTDTERGEEEEEEETLVNIVPKWKALNITELALWTPTLSEEQPPPEGQGQEEPQGLTGVGDPSEDIQAEGFEGELEPRGADEDVDTFRQESQENSYDIDQGNLNFDEEPSDLQD
Tissue specificity:Expressed in the trachea, ependymal cells and oviduct (at protein level) (PubMed:32203505). Germ cell specific. Specifically expressed in testis, and to a lower extent in ovary. Not expressed in somatic tissues (PubMed:9578619). {ECO:0000269|PubMed:32203505, ECO:0000269|PubMed:9578619}.
Induction:
Developmental stage:During male germ cell development it is not detected until 12 days. Significant expression is detected from 14-day-old through to adult testis. Expression is first detected in the pachytene spermatocytes at stage V, becomes stronger from the late pachytene spermatocytes to round spermatid stage, and then gradually decreases as the morphogenesis proceeds further. Not expressed in germ cells located in the first layer of the seminiferous epithelium (spermatogonia, leptotene and zygotene spermatocytes). {ECO:0000269|PubMed:9578619}.
Protein families: