DNLI3_MOUSE P97386
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UniProt:P97386
Recommended name：DNA ligase 3
EC number：EC 6.5.1.1
Alternative names：(DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3)
Cleaved into：
GeneID：
Gene names (primary )：Lig3
Gene names (synonym )：
Gene names (ORF )：
Length：1015
Mass：113072
Sequence：MTLAFKILFPRNLCALGRKELCLFPEQNRWAAISQFSQWSETNLLGGCCLLQRRKPVLALQRGHLRPRATHLTFWPGSHVGLCTGPCAMAEQRFCVDYAKRGTAGCKKCKEKIVKGVCRIGKVVPNPFSESGGDMKEWYHIKCMFEKLERARATTKKIEDLTELEGWEELEDNEKEQISQHIADLSSKAAATPKKKAAVQAKLTTTGQVTSPVKGASFITSTNPRKFSGFSAAKPNNSEQAPSSPAPGTSLSASKCDPKHKDCLLREFRKLCAMVAENPSYNTKTQIIHDFLQKGSTGGFSDGFHGDVYLTVKLLLPGVIKSVYNLNDKQIVKLFSRIFNCNPDDMARDLEQGDVSETIRIFFEQSKSFPPAAKSLLTIQEVDAFLLHLSKLTKEDEQQQALQDIASRCTANDLKCIIRLIKHDLKMNSGAKHVLDALDPNAYEAFKASRNLQDVVERVLHNEQEVEKDPGRRRALRVQASLMTPVQPMLAEACKSIEYAMKKCPNGMFSEIKYDGERVQVHKKGDHFSYFSRSLKPVLPHKVAHFKDYIPKAFPGGQSMILDSEVLLIDNNTGKPLPFGTLGVHKKAAFQDANVCLFVFDCIYFNDVSLMDRPLCERRKFLHDNMVEIRNRIMFSEMKQVTKASDLADMINRVIREGLEGLVLKDVKGTYEPGKRHWLKVKKDYLNEGAMADTADLVVLGAFYGQGSKGGMMSIFLMGCYDPDSQKWCTVTKCAGGHDDATLARLQKELVMVKISKDPSKIPSWLKINKIYYPDFIVPDPKKAAVWEITGAEFSRSEAHTADGISIRFPRCTRIRDDKDWKSATNLPQLKELYQLSKDKADFAVVAGDEASPTTGGSSGENEGTAGSAGPCKGPPSKSSASAKTTEQKLNSPSSRGGIKPIPKHSPMKPGEKLAVKSSPVKVGMKRKATDETPCLKKVLLDVFTGVRLYLPPSTPDFKRLKRYFVAFDGDLVQEFDMGSATHVLGNREKNTDAQLVSSEWIWACIRKRRLIAPC
Tissue specificity：The alpha isoform is expressed in all tissues, while the beta isoform is expressed only in the testis.
Induction：
Developmental stage：During male germ cell differentiation, expression of the beta isoform begins in the later stages of meiotic prophase and ends in the round spermatid stage.
Protein families：ATP-dependent DNA ligase family