NOGG_MOUSE   P97466


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UniProt:P97466

Recommended name:Noggin

EC number:

Alternative names:

Cleaved into:

GeneID:18121

Gene names  (primary ):Nog

Gene names  (synonym ):

Gene names  (ORF ):

Length:232

Mass:25770

Sequence:MERCPSLGVTLYALVVVLGLRAAPAGGQHYLHIRPAPSDNLPLVDLIEHPDPIFDPKEKDLNETLLRSLLGGHYDPGFMATSPPEDRPGGGGGPAGGAEDLAELDQLLRQRPSGAMPSEIKGLEFSEGLAQGKKQRLSKKLRRKLQMWLWSQTFCPVLYAWNDLGSRFWPRYVKVGSCFSKRSCSVPEGMVCKPSKSVHLTVLRWRCQRRGGQRCGWIPIQYPIISECKCSC

Tissue specificity:Expressed in condensing cartilage and immature chondrocytes. {ECO:0000269|PubMed:9603738}.

Induction:

Developmental stage:Embryonic expression was first detected in the node at 7.5 dpc. By early somite stages, expression extends anteriorly along the entire length of the notochord and is expressed in the dorsal neural tube from the caudal hindbrain to the posterior-most region of the embryo. By the time cranial tube closure is completed expression is continuous along most of the dorsal midline of the neural tube, to its rostral termination at the base of the forebrain. Expression in the neural tube and caudal notochord remains unchanged during early organogenesis from 9.5 dpc to 10.5 dpc. {ECO:0000269|PubMed:9585504}.

Protein families:Noggin family