OTUL_MOUSE Q3UCV8
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UniProt:Q3UCV8
Recommended name:Ubiquitin thioesterase otulin
EC number:EC 3.4.19.12
Alternative names:(Deubiquitinating enzyme otulin) (OTU domain-containing deubiquitinase with linear linkage specificity) (Ubiquitin thioesterase Gumby)
Cleaved into:
GeneID:432940
Gene names (primary ):Otulin
Gene names (synonym ):Fam105b Gum
Gene names (ORF ):
Length:352
Mass:40320
Sequence:MSRGTMPQPGAWPGASCAETPAREAGAAARDGGKVTAGAQPRAATRCPAEHEEDMYRAADEIEKEKELLIHERGISEPRLSVAPEMDIMDYCKKEWRGNTQKATCMKKGYEEVSQKFTSIRRVRGDNYCALRATLFQAMSQLAELPPWLQDLELILLPEKLINKYTWIKQWKLGLKFDGKSEDLVEKIKESLALLRKKWVSLAAMKTAEARQTACDELFTNEEEEYSLYEAVKFLMLNRAIELYDDKEKGKEVPFFSVLLFARDTSNDPEQLLRNHLNQVGHTGGLEQVEMFLLAYAVRHSIRVYRLSKYNTEEFITVYPTDPPKDWPMVTLIAEDDRHYNIPVRVCEETSV
Tissue specificity:
Induction:
Developmental stage:Enriched in a subset of endothelial cells near presumptive tips of vessels and vascular buds (at protein level). {ECO:0000269|PubMed:23708998}.
Protein families:Peptidase C65 family, Otulin subfamily