PIAS3_MOUSE   O54714


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UniProt:O54714

Recommended name:E3 SUMO-protein ligase PIAS3

EC number:EC 2.3.2.-

Alternative names:(E3 SUMO-protein transferase PIAS3) (Protein inhibitor of activated STAT protein 3)

Cleaved into:

GeneID:229615

Gene names  (primary ):Pias3

Gene names  (synonym ):

Gene names  (ORF ):

Length:628

Mass:68318

Sequence:MAELGELKHMVMSFRVSELQVLLGFAGRNKSGRKHELLAKALHLLKSSCAPSVQMKIKELYRRRFPRKTLGPSDLSLLSLPPGTSPVGSPGPLAPIPPTLLTPGTLLGPKREVDMHPPLPQPVHPDVTMKPLPFYEVYGELIRPTTLASTSSQRFEEAHFTFALTPQQLQQILTSREVLPGAKCDYTIQVQLRFCLCETSCPQEDYFPPNLFVKVNGKLCPLPGYLPPTKNGAEPKRPSRPINITPLARLSATVPNTIVVNWSSEFGRNYSLSVYLVRQLTAGTLLQKLRAKGIRNPDHSRALIKEKLTADPDSEVATTSLRVSLMCPLGKMRLTVPCRALTCAHLQSFDAALYLQMNEKKPTWTCPVCDKKAPYESLIIDGLFMEILNSCSDCDEIQFMEDGSWCPMKPKKEASEVCPPPGYGLDGLQYSAVQEGIQPESKKRVEVIDLTIESSSDEEDLPPTKKHCPVTSAAIPALPGSKGALTSGHQPSSVLRSPAMGTLGSDFLSSLPLHEYPPAFPLGADIQGLDLFSFLQTESQHYGPSVITSLDEQDTLGHFFQYRGTPSHFLGPLAPTLGSSHRSSTPAPPPGRVSSIVAPGSSLREGHGGPLPSGPSLTGCRSDVISLD

Tissue specificity:Expressed in kidney, heart, spleen, brain and cerebellum; weak expression, if any, in liver and lung. {ECO:0000269|PubMed:10854042, ECO:0000269|PubMed:14596924}.

Induction:

Developmental stage:Expressed as early as 7.6 dpc. Expression remains high through 15.5 dpc. {ECO:0000269|PubMed:10854042}.

Protein families:PIAS family


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