TTC8_MOUSE Q8VD72
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UniProt:Q8VD72
Recommended name:Tetratricopeptide repeat protein 8
EC number:
Alternative names:(TPR repeat protein 8) (Bardet-Biedl syndrome 8 protein homolog)
Cleaved into:
GeneID:76260
Gene names (primary ):Ttc8
Gene names (synonym ):Bbs8
Gene names (ORF ):
Length:515
Mass:58440
Sequence:MGSEMEPLLRAWSYFRRRKFQLCADLCTQMLEKSPYDQEPAPDLPVSQAAWILKARALTEMVYIDEIDVDQEGIAEMILDENAIAQVPRPGTSLKLPGTNQTGGPTQAVRPITQAGRPITGFLRPSTQSGRPGTMEQAIRTPRTAYTARPITSSSGRFVRLGTASMLTSPDGPFINLSRLNLTKYSQKPKLAKALFEYILHHENDVKMALDLASLSTEYSQYKDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQTASSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQKSEVAFPEHVDTQHLIKQLKQHFAML
Tissue specificity:Isoform 1 is retina-specific whereas isoform 2 is ubiquitously expressed. {ECO:0000269|PubMed:20451172}.
Induction:
Developmental stage:Expressed at 12 dpc in ciliated structures, including maturing (stages X and XI) spermatids, the connecting cilium of the retina and bronchial epithelial cells. At 14 and 16 dpc, detected in the telencephalon, with prominent expression at the developing ependymal cell layer and the olfactory epithelium. {ECO:0000269|PubMed:14520415}.
Protein families: