TTC8_MOUSE   Q8VD72


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UniProt:Q8VD72

Recommended name:Tetratricopeptide repeat protein 8

EC number:

Alternative names:(TPR repeat protein 8) (Bardet-Biedl syndrome 8 protein homolog)

Cleaved into:

GeneID:76260

Gene names  (primary ):Ttc8

Gene names  (synonym ):Bbs8

Gene names  (ORF ):

Length:515

Mass:58440

Sequence:MGSEMEPLLRAWSYFRRRKFQLCADLCTQMLEKSPYDQEPAPDLPVSQAAWILKARALTEMVYIDEIDVDQEGIAEMILDENAIAQVPRPGTSLKLPGTNQTGGPTQAVRPITQAGRPITGFLRPSTQSGRPGTMEQAIRTPRTAYTARPITSSSGRFVRLGTASMLTSPDGPFINLSRLNLTKYSQKPKLAKALFEYILHHENDVKMALDLASLSTEYSQYKDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQEMVDTFLYLAKVYIILDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNSSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEVALRFYRRLLQMGVYNCQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHIAVGIGDTNLAHQCFRLALVHNNHHAEAYNNLAVLEMRKGHVEQARALLQTASSLAPHMYEPHFNFATVSDKIGDLQRSYVAAQKSEVAFPEHVDTQHLIKQLKQHFAML

Tissue specificity:Isoform 1 is retina-specific whereas isoform 2 is ubiquitously expressed. {ECO:0000269|PubMed:20451172}.

Induction:

Developmental stage:Expressed at 12 dpc in ciliated structures, including maturing (stages X and XI) spermatids, the connecting cilium of the retina and bronchial epithelial cells. At 14 and 16 dpc, detected in the telencephalon, with prominent expression at the developing ependymal cell layer and the olfactory epithelium. {ECO:0000269|PubMed:14520415}.

Protein families:


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