RUSC1_MOUSE Q8BG26
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UniProt:Q8BG26
Recommended name:RUN and SH3 domain-containing protein 1
EC number:
Alternative names:
Cleaved into:
GeneID:72296
Gene names (primary ):Rusc1
Gene names (synonym ):
Gene names (ORF ):
Length:893
Mass:95195
Sequence:MLSPQRALLCNLNHIHLQHVSLGLHLSRRPELREGPLSTPPPPGDTGGKESRGPCSGTLVDANSNSPAVPCRCCQEHGSSIENQQDPSQEEEAVSPSDPGCSSSLSSCSDLSPDESPVSVYSRDLPGNEDANPQPSTLELGSPLAPAGPSTCSPDSFCCSPDSCSGISSPPGPDLDSNCNALTTCQDLPSPGLEEEEDSGEQDLATSELSETEDGRIDAGKAEPSWKINPIWKIDTEKTEAGWKTIEDSDSGRKTDENTNSSLKTESGKLASCLNTNSGSKIDAGKTDGGWRGDVSQEPVPHRTITSFHELAQKRKRGPGLPLVPQAKKDRSDWLIVFSPDTELPPTGSLGGSLAPPREVTTFKELRSRSRAQPPPVPPRDPPAGWALVPPRPPPPPVPPRRKKNRLGLQPIAEGLSEEGRAASPRAGEEASASQEPEEPRAHAVVRSSWSFAGVPGAQRLWMAEAQSGTGQLQEQKKGLLIAVSASVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADGLKPFRKDLITGQRRSSPWSVVEASVKPGSCTHSMGSLYSQVSRLAPLSSSRSRFHAFILGLLNTKQLELWFSSLQEDAGLLSLLYLPTGFFSLARGSCPSLATELLLLLQPLSVLTFHLDLLFEHHHHLPVGLQQAPAPSCPPPALQQTMQAVLHWGERLAQSLRGTSGESTTDSSTPSARPPAGSWWDQLTQASRVYASGGTEGFPLLRWGPRRHGTTAEAAQEAPPPTEQTTPGRSVWLGRLFGVPGCPSETESGAFKSRRPSSWLPPTVSVLALVKRGTPPETPPEALVSSPGSVVQADRAVRALCDHTAAGPDQLSFQRGELLRVIATVDEDWLRCGRDGVEGLVPVGYTSLVL
Tissue specificity:Expressed in brain, brain stem and spinal chord (at protein level).
Induction:
Developmental stage:Expressed at 15 dpc in hippocampal, cortical and cerebellar brain, and brain stem and spinal chord. At 18 dpc, expression strongly overlaps with TUBB3 expression in post-mitotic neurons throughout the entire brain. Expression levels increase to 18 dpc/P1 after which the levels decline in the hippocampus, cerebellum and brain stem and spinal chord into adulthood while remaining high in the cortex. {ECO:0000269|PubMed:22404429}.
Protein families: